Monthly Archives: May 2012

Cannabis and amyotrophic lateral sclerosis: hypothetical and practical applications, and a call for clinical trials

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“Cannabis and amyotrophic lateral sclerosis… Significant advances have increased our understanding of the molecular mechanisms of amyotrophic lateral sclerosis (ALS)… It appears that a number of abnormal physiological processes occur simultaneously in this devastating disease. Ideally, a multidrug regimen… would be required to comprehensively address the known pathophysiology of ALS.REMARKABLY, CANNABIS APPEARS to have activity in all of those areas. Preclinical data indicate that cannabis has POWERFUL antioxidative, anti-inflammatory, and neuroprotective effects… Based on the currently available scientific data, it is reasonable to think that cannabis might significantly slow the progression of ALS, potentially extending LIFE expectancy and substantially reducing the overall burden of the disease.”

http://www.ncbi.nlm.nih.gov/pubmed/20439484

Single-dose Pharmacokinetics and Tolerability of Oral Delta-9-Tetrahydrocannabinol in Patients with Amyotrophic Lateral Sclerosis

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“Single-dose Pharmacokinetics and Tolerability of Oral Delta-9-Tetrahydrocannabinol in Patients with Amyotrophic Lateral Sclerosis… Cannabinoids exert neuroprotective and symptomatic effects in amyotrophic lateral sclerosis (ALS)…”

http://www.ncbi.nlm.nih.gov/pubmed/22594565  

Cannabis oil is a highly efficient natural cancer cure

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“The study concluded that via the same biochemical process THC could terminate multiple types of cancers, affecting various cells in the body. Other studies have shown that cannabinoids may work by various mechanisms, including inhibiting cell growth, inducing cell death, and inhibiting tumor metastasis.
What stands out is that from the vast amount of research and data available, as well as the personal experiences of cancer survivors, is that no chemotherapy currently being used medically can match the non-toxic anti-carcinogenic and anti-tumorigenic effects of these natural plant compounds.”

Click here to learn more and see full article

Rheumatoid arthritis, cannabis based medicine eases pain and suppresses disease

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“The first study to use a cannabis-based medicine (CBM) for treating rheumatoid arthritis has found that it has a significant effect on easing pain and on suppressing the disease”

http://www.medicalnewstoday.com/releases/33376.php

The Cannabinergic System as a Target for Anti-inflammatory Therapies

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“Cell-based experiments or in vivo animal testing suggest that regulation of the endocannabinoid circuitry can impact almost every major function associated with the immune system. These studies were assisted by the development of numerous novel molecules that exert their biological effects through the endocannabinoid system. Several of these compounds were tested for their effects on immune function, and the results suggest therapeutic opportunities for a variety of inflammatory diseases such as multiple sclerosis, rheumatoid arthritis, inflammatory bowel disease, atherosclerosis, allergic asthma, and autoimmune diabetes through modulation of the endocannabinoid system.”

http://www.ingentaconnect.com/content/ben/ctmc/2006/00000006/00000013/art00008