News: Can marijuana treat the symptoms of Crohn’s Disease?

“A new study, published in the journal Clinical Gastroenterology and Hepatology, suggests that cannabis could help relieve symptoms of Crohn’s Disease, a lifelong chronic illness that causes abdominal pain, cramping, diarrhea, nausea, vomiting, weight loss and lack of energy.”

News: Can marijuana treat the symptoms of Crohn

“That’s good news for sufferers, especially considering there is currently no cure.

Researchers studied 21 patients with Crohn’s Disease. Participants were randomly assigned to one of two groups: The first group was given cannabis cigarettes twice a day, the second group was given a  placebo containing cannabis flowers from which the THC had been removed.

“A short course (8 week) of THC-rich cannabis produced significant clinical, steroid-free benefits to 11 patients with active CD, compared to placebo, without side effects,” the study’s authors wrote.

The most promising part?

“Complete remission was achieved by 5/11 subjects in the cannabis group.”

Crohn’s patients aren’t the only ones who can benefit from marijuana’s medical properties, according to new research.

A recent study published in the American Journal of Medicine, suggests that marijuana can lower the risk of diabetes as well.

Marijuana users have lower fasting insulin levels, Murray Mittleman, associate professor of medicine at Harvard Medical School and the lead author of the study told Time Healthland. They are “less resistant to the insulin produced by their body to maintain a normal blood sugar level,”he says.

According to Health Canada, medical marijuana can also be used to manage symptoms like severe pain, cachexia, anorexia, weight loss, and severe nausea from cancer; arthritis pain; seizures from epilepsy; and pain and muscle spasms from spinal cord injuries and multiple sclerosis.”

More:http://www.besthealthmag.ca/blog/post/news-can-marijuana-cure-crohns-disease

Marijuana May Smoke Out Crohn’s Disease Symptoms

“Crohn’s Disease treatment in the form of medical marijuana may result in a complete remission of symptoms in some people. A new study researched the effects of marijuana on this chronic condition that affects the digestive tract.”

Medical marijuana products are displayed at a medical dispensary
 
“Symptoms of the bowel condition include persistent diarrhea, rectal bleeding, abdominal cramps and pain. Crohn’s Disease can also cause severe vomiting, weight loss and arthritis. The feeling of low energy and fatigue is also common among people who suffer from Crohn’s Disease.
 
 Medical marijuana used as treatment has a significant effect on the symptoms of Crohn’s Disease, according to a new study.
 

In the very first placebo-controlled trial, researchers found that medical marijuana can reduce the symptoms of Crohn’s disease or eliminate them all together. Results of the study were published in the journal Clinical Gastroenterology and Hepatology.”

Read more: http://www.itechpost.com/articles/9298/20130516/marijuana-smoke-out-crohns-disease-symptoms.htm

Marijuana may help patients with Crohn’s disease, study says

“New research published earlier this month might have more patients with Crohn’s disease turning to medical marijuana for relief.”
 
Crohn’s disease is an inflammatory bowel disease that affects around 500,000 people in North America.

 

In a first-of-its-kind clinical trial, an 8-week treatment regimen involving daily smoking of marijuana ‘cigarettes’ resulted in a reduction in overall disease severity in 10 of the 11 patients that were studied. 5 of these patients experienced complete remission of their disease.

 

The results were published online in the journal Clinical Gastroenterology and Hepatology and authored by scientists at the Meir Medical Clinical in Israel. Israel has one of the most fastest growing medical marijuana programs in the world, with over 11,000 registered patients as of today — up from just 400 in 2009.

 

While the researchers say that their study was the first placebo-controlled trial — the “gold standard” when it comes to medical research — to investigate the effects of marijuana use on patients with Crohn’s disease, other studies have produced similar results.

 

Based on findings from both animal and human research, experts suggest that cannabis could play a role in the treatment of Crohn’s and other inflammatory bowel diseases by regulating intestinal hyperactivity, inflammation and pain.

 

Marijuana’s medical properties come directly from compounds known as cannabinoids, including the well-known tetrahydrocannabinol (THC) molecule. Interestingly, the cannabinoids found in the cannabis plant have been shown to mimic the activity of endocannabinoids – cannabinoids that are produced naturally by the human body.

 

Similarly, studies have identified a variety of digestive functions that can be modulated by cannabinoid activity, especially in inflammatory disease states.

 

Although the findings of the current study provide considerable support for the use of marijuana as a Crohn’s disease treatment, the authors call for more studies to “look into the role of cannabinoids in controlling inflammation and symptoms in inflammatory bowel disease.”

 

Indeed, larger studies may be able to provide stronger confirmation or perhaps refute the findings of the newest study, which failed to demonstrate complete remission of Crohn’s in the majority of the treatment group.

 

Still, the authors concluded their research by stating, “a short course of THC-rich cannabis produced significant clinical, steroid-free benefits to 11 patients with active Crohn’s disease, compared to placebo, without side effects.””

http://www.digitaljournal.com/article/350495

Smoking Marijuana Causes ‘Complete Remission’ of Crohn’s Disease, No Side Effects, New Study Shows

“Marijuana – scientific name “cannabis” – performed like a champ in the first-ever placebo-controlled trial of the drug to treat Crohn’s Disease, also known as inflammatory bowel disease.”

 

“The disease of the digestive tract afflicts 400,000 – 600,000 people in North America alone causing abdominal pain, diarrhea (which can be bloody), severe vomiting, weight loss, as well as secondary skin rashes, arthritis, inflammation of the eye, tiredness, and lack of concentration.

Smoking pot caused a “complete remission” of Crohn’s disease compared to placebo in half the patients who lit up for eight weeks, according to clinical trial data to be published the journal Clinical Gastroenterology and Hepatology.

Researchers at Israel’s Meir Medical Center took 21 people with intractable, severe Crohn’s disease and gave 11 of them two joints a day for eight weeks. “The standardized cannabis cigarettes” contained 23 percent THC and 0.5 percent CBD (cannabidiol). (Such marijuana is available on dispensary shelves in San Francisco, Oakland, and other cities that have regulated access to the drug.) The other ten subjects smoked placebo cigarettes containing no active cannabinoids.

Investigators reported that smoking weed caused a “complete remission” of Crohn’s Disease in five of the 11 subjects. Another five of the eleven test subjects saw their Crohn’s Disease symptoms cut in half. Furthermore, “subjects receiving cannabis reported improved appetite and sleep, with no significant side effects.”

The study is the first placebo-controlled clinical trial to assess the consumption of cannabis for the treatment of Crohn’s, notes NORML. All of the patients had intractable forms of the disease and did not respond to conventional treatments. Still, the United States government claims that marijuana is as dangerous as heroin and has no medical use. U.S. Attorney Melinda Haag is waging a war on safe access to medical cannabis in the Bay Area.”

http://blog.sfgate.com/smellthetruth/2013/05/14/smoking-marijuana-cured-crohns-disease-with-no-side-effects-new-study-shows/

Marijuana Put My Crohn’s Disease Into Remission and It’s Not A Joke

Marijuana Put My Crohn’s Disease Into Remission and It’s Not A Joke

Choosing pot over pills may be the way to go for Crohn’s sufferers – MSN

A man smokes medical marijuana (© Rick Bowmer/AP)

“A new study published in the Clinical Gastroenterology and Hepatology journal shows that marijuana reduces the symptoms of Crohn’s disease, a condition affecting the bowel. Researchers at the Meir Medical Center in Israel rounded up 21 sufferers, 11 were instructed to smoke marijuana twice a day, while the other 10 were given placebo pot. Although that’s a fairly small test group, the results were pretty miraculous: Eight weeks later the stoners showed significant improvement and five had gone into remission. Unlike ingesting an endless stream of pills, researchers also revealed that partaking in a little ganja had “no significant side effects,” other than helping the group to sleep better and increasing their appetites.”

http://now.msn.com/marijuana-reduces-crohns-disease-symptoms-in-meir-medical-center-study#scpshrjp2

Cannabis Linked To Crohn’s Cure

“Smoking cannabis may be key in treating Crohn’s disease, research suggest.

In a recent trial marijuana was shown to induce ‘complete remission’ for patients suffering from the condition, which is also known as inflammatory bowel disease.

Scientists at Meir Medical Center, Israel, studied 21 people with severe Crohn’s disease who did not respond to various therapies.

They split the patients into two groups: 11 were given a joint to smoke twice a day for eight weeks, while 10 were given a placebo cigarette which contained no trace of cannabinoids.

A ‘complete remission’ of Crohn’s disease was recorded in 5/11 (45%) of the cannabis group and 1/10 in the placebo group.

A total of 10/11 patients in the cannabis group responded to the clinical trial with Crohn’s symptoms (which include pain, diarrhoea, tiredness and weight loss) significantly reduced.

In addition, study authors wrote: “Subjects receiving cannabis reported improved appetite and sleep, with no significant side effects.”

“Further studies, with larger patient groups and a non-smoking mode of intake, are warranted,” they added.”

http://www.huffingtonpost.co.uk/2013/05/21/cannabis-treatment-inflammatory-bowel-disease-crohns_n_3311278.html?utm_hp_ref=uk%3Fncid%3DGEP

Please Note: The title of this article has been changed to “Could Cannabis Cure Crohn’s Disease?”

Cannabidiol reduces cigarette consumption in tobacco smokers: Preliminary findings.

“The role of the endocannabinoid system in nicotine addiction is being increasingly acknowledged. We conducted a pilot, randomised double blind placebo controlled study set out to assess the impact of the ad-hoc use of cannabidiol (CBD) in smokers who wished to stop smoking.

24 smokers were randomised to receive an inhaler of CBD (n=12) or placebo (n=12) for one week, they were instructed to use the inhaler when they felt the urge to smoke.

 Over the treatment week, placebo treated smokers showed no differences in number of cigarettes smoked.

In contrast, those treated with CBD significantly reduced the number of cigarettes smoked by ~40% during treatment.

 Results also indicated some maintenance of this effect at follow-up.

 These preliminary data, combined with the strong preclinical rationale for use of this compound, suggest CBD to be a potential treatment for nicotine addiction that warrants further exploration.”

http://www.ncbi.nlm.nih.gov/pubmed/23685330

The association between cigarette smoking and drug abuse in the United States.

“Cigarette smoking has been identified as an independent risk factor for many human diseases. However, the association between cigarette smoking and illegal drug use has not been thoroughly investigated. We have analyzed the 1994 National Household Survey on Drug Abuse to clarify whether cigarette smoking has any effect on the initiation of illegal drug use…”

“This study suggests that cigarette smoking may be a gateway drug to illegal drug use.”

http://www.ncbi.nlm.nih.gov/pubmed/11110061

Study Adds to Evidence That Cigarettes Are Gateway to Marijuana

“Teen smokers who rationalize their use of cigarettes by saying, “At least, I’m not doing drugs,” may not always be able to use that line.

New research to be presented Sunday, May 5, at the Pediatric Academic Societies (PAS) annual meeting in Washington, DC, supports the theory that cigarettes are a gateway drug to marijuana.

“Contrary to what we would expect, we also found that students who smoked both tobacco and marijuana were more likely to smoke more tobacco than those who smoked only tobacco,” said study author Megan Moreno, MD, MSEd, MPH, FAAP, an investigator at Seattle Children’s Research Institute and associate professor of pediatrics at the University of Washington.

Dr. Moreno and her colleagues randomly selected incoming college students from two universities — one in the Northwest and one in the Midwest — to participate in the longitudinal study. Students were interviewed prior to entering college and again at the end of their freshman year regarding their attitudes, intentions and experiences with substances.

Specifically, students were asked if they had used tobacco or marijuana ever in their lives and in the past 28 days. Researchers also assessed the quantity and frequency of marijuana and tobacco use in the past 28 days.

Results showed that prior to entering college, 33 percent of the 315 participants reported lifetime tobacco use, and 43 percent of lifetime users were current users. In addition, tobacco users were more likely to have used marijuana than those who did not use tobacco.

By the end of their freshman year, 66 percent of participants who reported tobacco use prior to entering college remained current users with an average of 34 tobacco episodes per month. Of these, 53 percent reported concurrent marijuana use. Overall, users of both substances averaged significantly more tobacco episodes per month than current users of tobacco only (42 vs. 24).

“These findings are significant because in the past year we have seen legislation passed that legalizes marijuana in two states,” Dr. Moreno said. “While the impact of these laws on marijuana use is a critical issue, our findings suggest that we should also consider whether increased marijuana use will impact tobacco use among older adolescents.”

Future work should involve designing educational campaigns highlighting the increased risks of using these substances together, Dr. Moreno concluded.”

http://www.sciencedaily.com/releases/2013/05/130505073742.htm