“Several studies in cell cultures and in animal models have demonstrated that cannabinoids have important antitumoral properties… many of these effects are mediated through cannabinoid (CB) receptors CB1 and CB2…
The obtained data suggest a possible implication of the endocannabinoid system in renal carcinogenesis.”
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989249/
“Objective: To analyze the mRNA and protein expression of cannabinoid receptors CB1 and CB2 in chromophobe renal cell carcinoma (ChRCC) and renal oncocytoma (RO)…
Quantitative RT-PCR analysis showed that CB1 mRNA was underexpressed by 12-fold in ChRCC and had a variable expression in RO. CB1 protein showed intense positive immunostaining in both neoplasms. Both CB2 mRNA and protein were not expressed in tumor and non tumorrenal tissue.
This distinct immunoprofile may eventually be used as an additional tool with practical interest in the differential diagnosis of renal tumors.”
“It is even more evidence of our need for the government to stop punishing patients for using this relatively safe and non-toxic treatment method … ”
“For years, many Americans with HIV/AIDS have used medical marijuana to relieve some common symptoms associated with the illness such as nausea, vomiting and appetite loss.
Now, a new study published last week in the journal AIDS Researcher and Human Retroviruses found that a daily dosage of marijuana’s psychoactive ingredient tetrahydrocannabinol, or THC, may actually fight the HIV/AIDS virus itself.”
More: http://www.mintpressnews.com/hivaids-cure-may-be-found-in-marijuana-study/179398/
“Researchers are looking into the use of THC (tetrahydrocannabinol), the active ingredient in marijuana, to help stop the spread of HIV infection.
Hundreds of marijuana researchers have reported that THC was able to pierce the RIV virus in monkeys. That particular virus is almost identical to the HIV virus found in humans, so this news is very encouraging.
The greatest drawbacks to this excellent news are the current laws preventing testing on human candidates.
With the changing of these restrictive laws, HIV infections have a great chance of being cured, with cannabis as a real possible player in the race to stop the disease.”
More: http://guardianlv.com/2014/02/hiv-infections-cured-with-cannabis-a-real-possibility/
“According to a new study published in the journal PloS ONE, researchers from Mount Sinai School of Medicine discovered that marijuana-like compounds can inhibit the multiplication of human immunodeficiency virus (HIV) in late-stage AIDS by acting on viral receptors…
“We knew that cannabinoid drugs like marijuana can have a therapeutic effect in AIDS patients, but did not understand how they influence the spread of the virus itself. We wanted to explore cannabinoid receptors as a target for pharmaceutical interventions that treat the symptoms of late-stage AIDS and prevent further progression of the disease…”
“Medical cannabis is used as an appetite stimulant, antiemetic, antispasmodic and sometimes as analgesic to help treat chronic, non-cancerous pain, vomiting or nausea caused by chemotherapy. In some cases, it is also used to aid treating symptoms of AIDS patients…
Marijuana or “weed” is now among the several ingredients that researchers are looking into to helping stop further spread of HIV infection.”
“People with HIV (and other conditions) have used prescription marijuana to treat the side effects of medication, but a new study published in the journal AIDS Research and Human Retroviruses, recently showed that daily doses of may even help combat the disease.”
More: http://www.hivplusmag.com/research/2014/02/11/breaking-news-study-says-marijuana-may-stop-spread-hiv
“There’s been some interesting research on using THC (tetrahydrocannabinol), the principal psychoactive drug in marijuana, to help fight HIV, and damage cancer cells in some leukemias and possibly malignant tumors.
…the possibility exists that information from both of these research studies may produce beneficial results in the treatment of HIV and cancer.”
More: http://americablog.com/2014/02/marijuana-treatment-hiv-cancer.html
“But the U.S. government won’t let scientists try out this promising treatment on humans… proving that an illegal drug can stop a deadly disease in humans—without testing it on them—is impossible…
THC is one of 500 active ingredients in marijuana. And marijuana, despite many studies proving its medical value, is sill classified by the government as a Schedule 1 Substance.
In the face of mounting evidence that it is beneficial in treating diseases… it remains a controlled substance.
During HIV infection, one of the earliest effects is that the virus spreads rapidly throughout the body and kills a significant part of cells in the gut and intestine. This activity damages the gut in a way that allows the HIV to leak through the cell wall of the intestines and into the bloodstream.
When THC is introduced into this environment, it activates the CB2 receptors in the intestines to build new, healthy bacterial cells that block the virus from leaking through the cell walls. In other words, the body works hard to keep bad stuff in the intestines and the good stuff out.
Put another way: HIV kills the cells that protect the walls— THC brings them back. Reducing the amount of the virus in the lower intestines could then help keep uninfected people uninfected.”
More: http://www.thedailybeast.com/articles/2014/02/15/weed-can-block-h-i-v-s-spread-no-seriously.html
“Marijuana has long been used to effectively treat symptoms associated with HIV, such as chronic pain and weight loss. But a growing body of research suggests the plant may be able to stop the spread of the disease itself.”