Antiviral activity of medicinal plant-derived products against SARS-CoV-2

SAGE Journals

“This review presents information from several studies that have demonstrated the antiviral activity of extracts (Andrographis paniculataArtemisia annuaArtemisia afraCannabis sativaCurcuma longaEchinacea purpureaOlea europaeaPiper nigrum, and Punica granatum) and phytocompounds derived from medicinal plants (artemisinins, glycyrrhizin, and phenolic compounds) against SARS-CoV-2.

A brief background of the plant products studied, the methodology used to evaluate the antiviral activity, the main findings from the research, and the possible mechanisms of action are presented.

These plant products have been shown to impede the adsorption of SARS-CoV-2 to the host cell, and prevent multiplication of the virus post its entry into the host cell. In addition to antiviral activity, the plant products have also been demonstrated to exert an immunomodulatory effect by controlling the excessive release of cytokines, which is commonly associated with SARS-CoV-2 infections.”

https://pubmed.ncbi.nlm.nih.gov/35894129/

https://journals.sagepub.com/doi/10.1177/15353702221108915

“Antimicrobial and Antiviral (SARS-CoV-2) Potential of Cannabinoids and Cannabis sativa: A Comprehensive Review”

https://pubmed.ncbi.nlm.nih.gov/34885798/

“Anti-Inflammatory and Antiviral Effects of Cannabinoids in Inhibiting and Preventing SARS-CoV-2 Infection”

https://pubmed.ncbi.nlm.nih.gov/35456990/

“Cannabinoids Block Cellular Entry of SARS-CoV-2 and the Emerging Variants”

https://pubmed.ncbi.nlm.nih.gov/35007072/

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