“The function of the endocannabinoid system (ECS) in the renal tissue is not completely understood.

We studied the effect of compounds modulating the activity of cannabinoid CB receptors on the active reabsorption of Na+ in LLC-PK1 cells.

CONCLUSION AND IMPLICATIONS: ECS is expressed in LLC-PK1 cells. Both TRPV1 and CB1 regulate (Na++K+)-ATPase activity in these cells, and are modulated by lipid and peptide CB1 ligands, which act via different signaling pathways”

.http://www.ncbi.nlm.nih.gov/pubmed/25537261