“Cannabidiol (CBD), a major non-psychotomimetic constituent of Cannabis sativa, has therapeutic potential for certain psychiatric and neurological disorders.
Studies in laboratory animals and limited human trials indicate that CBD has anticonvulsant and neuroprotective properties.
Its effects against cocaine neurotoxicity, however, has remained unclear. Thus, the present study tested the hypothesis that CBD protects against cocaine-induced seizures and investigated the underlying mechanisms.
In conclusion, CBD protects against seizures in a model of cocaine intoxication.
CBD should be further investigated as a strategy for alleviating psychostimulant toxicity.”