“Bone marrow derived mesenchymal stem cells (BM-MSCs) are considered as the most promising cells source for bone engineering.

Cannabinoid(CB) receptors play important roles in bone mass turnover.

The aim of this study is to test if activation of CB2 receptor by chemical agonist could enhance the osteogenic differentiation and mineralization in bone BM-MSCs…

Taken together, data from this study suggested that activation of CB2 receptor plays important role in osteogenic differentiation of BM-MSCs.

Lack of CB2 receptor may be related to osteoporosis.

These results demonstrate that the activation of CB2 signaling is essential for the maintenance of normal bone mass.

Manipulating CB2 signaling may offer a molecular tool for the increasing osteogenic differentiation of stem cells.”

http://www.hindawi.com/journals/bmri/2015/874982/

http://www.thctotalhealthcare.com/category/osteoporosis-2/