Anandamide mediates cognitive judgement bias in rats.

“In the present study, we investigated the effects of acute pharmacological manipulation of the endocannabinoid (EC) system on the valence of cognitive judgement bias of rats in the ambiguous-cue interpretation (ACI) paradigm.

Our findings suggest involvement of the endocannabinoid system in the mediation of optimistic judgement bias.”

http://www.ncbi.nlm.nih.gov/pubmed/26363193

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