“Effects of the medicinal mushroom Agaricus blazei Murill on immunity, infection and cancer. Agaricus blazei Murill (AbM) is an edible, medicinal mushroom of Brazilian origin. It is used traditionally against a range of diseases, including cancer…”  http://www.ncbi.nlm.nih.gov/pubmed/18782264

“Suppressing effects of daily oral supplementation of beta-glucan extracted from Agaricus blazei Murill on spontaneous and peritoneal disseminated metastasis in mouse model. The Basidiomycete fungus Agaricus blazei Murill has traditionally been used as a health food for the prevention of cancer. Treatment with beta-glucan may be beneficial for cancer patients with or at risk for metastasis. The beta-glucan-dependent signaling pathways are critical for our understanding of anticancer events and development of cancer therapeutic agents.”  http://www.ncbi.nlm.nih.gov/pubmed/15883813

“Selective tumoricidal effect of soluble proteoglucan extracted from the basidiomycete, Agaricus blazei Murill, mediated via natural killer cell activation and apoptosis.” http://www.ncbi.nlm.nih.gov/pubmed/9625538

“Tumoricidal effects of beta-glucans: mechanisms include both antioxidant activity plus enhanced systemic and topical immunity. These results indicate the A. blazei extract may enhance not only the immnunomodulatory effects that promote activity of peritoneal exudate cells for tumor regression but also potentially result in the direct destruction of tumor cells through its antioxidant activity.”  http://www.ncbi.nlm.nih.gov/pubmed/18791933

“Anti-tumor polysaccharide from the mycelium of liquid-cultured Agaricus blazei mill.” http://www.ncbi.nlm.nih.gov/pubmed/10319424

“Agaritine from Agaricus blazei Murrill induces apoptosis in the leukemic cell line…Agaricus blazei Murrill (ABM) has been shown to exhibit immunostimulatory and anti-cancer activities…This is the first report suggesting that the anti-tumor effect of agaritine is mediated through apoptosis (programmed cell death). The present results might provide helpful suggestions for the design of anti-tumor drugs toward leukemia patients.” http://www.ncbi.nlm.nih.gov/pubmed/21382445

“An extract of Agaricus blazei Murill administered orally promotes immune responses in murine leukemia BALB/c mice in vivo.. The edible mushroom (fungus) Agaricus blazei Murill (ABM) is a health food in many countries. Importantly, it has been shown to have antitumor and immune effects…ABM extract is likely to stimulate immunocytes and regulate immune response in leukemia mice in vivo.”  http://www.ncbi.nlm.nih.gov/pubmed/22637937

“The Mushroom Agaricus blazei Murill Elicits Medicinal Effects on Tumor, Infection, Allergy, and Inflammation through Its Modulation of Innate Immunity and Amelioration of Th1/Th2 Imbalance and Inflammation…The medicinal mushroom Agaricus blazei Murill from the Brazilian rain forest has been used in traditional medicine and as health food for the prevention of a range of diseases, including infection, allergy, and cancer.”  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168293/

“Isolation of an antitumor compound from Agaricus blazei Murill and its mechanism of action…This is the first report of ergosterol as an antiangiogenic substance.”  http://jn.nutrition.org/content/131/5/1409.long

“Isolation of an anti-angiogenic substance from Agaricus blazei Murill: its antitumor and antimetastatic actions…This is the first report showing that sodium pyroglutamate isolated from A. blazei as an anti-angiogenic substance has potent antitumor and antimetastatic actions, as well as immune-modulatory activity…”  http://www.ncbi.nlm.nih.gov/pubmed/15471563

“A low molecular weight polysaccharide isolated from Agaricus blazei Murill (LMPAB) exhibits anti-metastatic effect… indicating the potential of its clinical application for the prevention and treatment of cancer metastasis.” http://www.ncbi.nlm.nih.gov/pubmed/19885951

“Immunostimulatory activities of a low molecular weight antitumoral polysaccharide isolated from Agaricus blazeiMurill (LMPAB) in Sarcoma tumor-bearing mice”  http://www.ncbi.nlm.nih.gov/pubmed/19694186

“In vivo growth-inhibition of Sarcoma by an alpha–glucan-beta–glucan-protein complex polysaccharide obtained from Agaricus blazei Murill…this polysaccharide probably could explain the ethnopharmacological use of this mushroom in the treatment of cancer.” http://www.ncbi.nlm.nih.gov/pubmed/18726068

“Antitumor beta glucan from the cultured fruit body of Agaricus blazei.”  http://www.ncbi.nlm.nih.gov/pubmed/11456124

“Inhibitory mechanisms of Agaricus blazei Murill on the growth of prostate cancer in vitro and in vivo…A. blazei might have potential therapeutic use in the prevention and treatment of human prostate cancer.”  http://www.ncbi.nlm.nih.gov/pubmed/18926679

“Phase I Clinical Study of the Dietary Supplement, Agaricus blazei Murill (ABM), in Cancer Patients in Remission… This trial supports previous evidence that the ABM product is generally safe, excluding possible allergic reaction.”  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092499/

“Quality of life improvements among cancer patients in remission following the consumption of Agaricus blazei Murill mushroom extract.”  http://www.ncbi.nlm.nih.gov/pubmed/24050580