Cannabidiol (CBD) enhanced the hippocampal immune response and autophagy of APP/PS1 Alzheimer’s mice uncovered by RNA-seq

 Life Sciences“Alzheimer’s disease (AD) is a central nervous system disease characterized by dementia, which has now become a major threat to global health.

Cannabidiol (CBD) is a natural component extracted from the hemp plant and exhibits multiple mechanisms to improve the pathological process of AD in vitro and in vivo. However, its underlying molecular mechanism is still unclear.

This study attempts to reveal its common mechanism through transcriptome sequence.

This study illustrated that CBD may improve the pathological process of AD by enhancing immune system response and autophagy pathway.”

https://pubmed.ncbi.nlm.nih.gov/33096116/

https://www.sciencedirect.com/science/article/abs/pii/S0024320520313771?via%3Dihub

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