“Novel antimicrobial drugs are urgently needed to counteract the increasing occurrence ofbacterial resistance.
Extracts of Cannabis sativa have been used for the treatment of several diseases since ancient times. However, its phytocannabinoid constituents are predominantly associated with psychotropic effects and medical applications far beyond the treatment of infections.
It has been demonstrated that several cannabinoids show potent antimicrobial activity against primarily Grampositive bacteria including methicillin-resistant Staphylococcus aureus (MRSA).
As first in vivo efficacy has been demonstrated recently, it is time to discuss whether cannabinoids are promising antimicrobial drug candidates or overhyped intoxicants with benefits.”