“Coffee protects against breast cancer recurrence, detailed findings confirm” http://www.sciencedaily.com/releases/2015/04/150421084531.htm
“Long-term night work linked to higher breast cancer risk” http://www.ctvnews.ca/health/health-headlines/long-term-night-work-linked-to-higher-breast-cancer-risk-1.1349734
“Study Examines Link Between Breast Cancer and Diabetes” http://healthyliving.msn.com/diseases/breast-cancer/study-examines-link-between-breast-cancer-and-diabetes
“Menopause Hormone Linked to Breast Cancer” http://www.nytimes.com/1989/08/03/us/menopause-hormone-linked-to-breast-cancer.html
“Sugar Intake and Breast Cancer Risk”
“Prolonged sitting linked to breast cancer, colon cancer” http://inthenews.mayoclinic.org/2011/11/03/prolonged-sitting-linked-to-breast-cancer-colon-cancer/
“The fatter a woman becomes, the higher her risk of breast cancer” http://www.wwl.com/The-fatter-a-woman-becomes-the-higher-her-risk-of-/20003707
“Obesity Fuels Breast Ca by Altering Tissue Microenvironment” http://www.clinicaloncology.com/ViewArticle.aspx?d=Web%2BExclusives&d_id=245&i=September+2015&i_id=1224&a_id=33552
“Exercise, weight control reduce risk of breast cancer” http://www.usatoday.com/story/news/nation/2013/10/01/breast-cancer-exercise-weight-control/2795127/
“How Exercise May Reduce Breast Cancer Risk ” http://news.health.com/2013/04/09/new-clues-to-how-exercise-may-reduce-breast-cancer-risk/
“Control of Breast Cancer by the Endocannabinoid System”
http://grantome.com/grant/NIH/K01-CA111723-01A2
“Exercise activates the endocannabinoid system”
http://www.ncbi.nlm.nih.gov/pubmed/14625449
“The endocannabinoid system and cancer: therapeutic implication”
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3165955/..
.”Exercise Helps Prevent Breast Cancer”
http://abcnews.go.com/Health/story?id=116923&page=
“Walking Can Reduce Breast Cancer Risk”
http://healthland.time.com/2013/10/04/walking-can-reduce-breast-cancer-risk/
“Breast Cancer May Be Linked to Digestion” http://www.care2.com/greenliving/breast-cancer-may-be-linked-to-digestion.html
“Design a healthy diet to help reduce breast cancer risk” http://www.tauntongazette.com/article/20140930/LIFESTYLE/140939803
“High fat diet linked to breast cancer” http://www.theguardian.com/uk/2003/jul/18/research.sciencenews
“Hunger linked to increased risk of breast cancer in women” http://www.news-medical.net/news/20120926/Hunger-linked-to-increased-risk-of-breast-cancer-in-women.aspx
“Cannabinoids: a new hope for breast cancer therapy? … cannabinoids, the active components of Cannabis sativa… possess anticancer activity. Thus, these compounds exert anti-proliferative, pro-apoptotic, anti-migratory and anti-invasive actions in a wide spectrum of cancer cells… Moreover, tumor growth, angiogenesis and metastasis are hampered by cannabinoids… cannabinoid-based medicines may be useful for the treatment of most breast tumor subtypes.” http://www.ncbi.nlm.nih.gov/pubmed/22776349
“Synthetic cannabinoid receptor agonists inhibit tumor growth and metastasis of breast cancer.” http://www.ncbi.nlm.nih.gov/pubmed/19887554
“Here, we show that Δ9-tetrahydrocannabinol (THC), through activation of CB2 cannabinoid receptors, reduces human breast cancer cell proliferation by blocking the progression of the cell cycle and by inducing apoptosis.” http://www.ncbi.nlm.nih.gov/pubmed/16818634
“Δ9-Tetrahydrocannabinol Inhibits Cell Cycle Progression in Human Breast Cancer Cells through Cdc2 Regulation.. Taken together, these data might set the bases for a cannabinoid therapy for the management of breast cancer.” http://cancerres.aacrjournals.org/content/66/13/6615.long
“Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition… ErbB2-positive breast cancer is characterized by highly aggressive phenotypes and reduced responsiveness to standard therapies…The purpose of this study was to determine whether cannabinoids might constitute a new therapeutic tool for the treatment of ErbB2-positive breast tumors… Our results show that both Delta9-tetrahydrocannabinol, the most abundant and potent cannabinoid in marijuana, and JWH-133, a non-psychotropic CB2 receptor-selective agonist, reduce tumor growth, tumor number, and the amount/severity of lung metastases… Histological analyses of the tumors revealed that cannabinoids inhibit cancer cell proliferation, induce cancer cell apoptosis, and impair tumor angiogenesis. Cannabinoid antitumoral action… these results provide a strong preclinical evidence for the use of cannabinoid-based therapies for the management of ErbB2-positive breast cancer.” http://www.molecular-cancer.com/content/9/1/196
“Use of cannabinoid receptor agonists in cancer therapy as palliative and curative agents… not only as palliative but also as curative drugs.” http://www.ncbi.nlm.nih.gov/pubmed/19285265
“New Research Shows How Marijuana Compound Can Reduce Tumor Growth In Cancer Patients…THC, the major active component of marijuana, has anti-cancer properties,” http://www.huffingtonpost.com/2014/07/16/marijuana-tumors_n_5588639.html
“Marijuana compound could help fight breast cancer” http://abclocal.go.com/kgo/story?id=5771385
“Cannabis compound stops spread of breast cancer: researchers” http://www.cbc.ca/news/technology/cannabis-compound-stops-spread-of-breast-cancer-researchers-1.675379
“Down-regulation of cyclooxygenase-2 (COX-2) by cannabidiolic acid in human breast cancer cells. Cyclooxygenase-2 (COX-2) is involved not only in inflammatory processes, but also in the metastasis of cancer cells… cannabidiolic acid (CBDA), a selective COX-2 inhibitor found in the fiber-type cannabis plant…Taken together, the results obtained here demonstrated that i) CBDA had dual inhibitory effects on COX-2 through down-regulation and enzyme inhibition, and ii) CBDA may possess the ability to suppress genes that are positively involved in the metastasis of cancer cells in vitro.”http://www.ncbi.nlm.nih.gov/pubmed/25242400
“Cannabidiolic acid as a selective cyclooxygenase-2 inhibitory component in cannabis…Taken together, these lines of evidence in this study suggest that naturally occurring CBDA in cannabis is a selective inhibitor for COX-2.” http://dmd.aspetjournals.org/content/36/9/1917.long
“Cannabidiolic acid, a major cannabinoid in fiber-type cannabis, is an inhibitor of MDA-MB-231 breast cancer cell migration… Cannabidiol (CBD)… anti-proliferative effect on cancer cells…CBD is obtained from non-enzymatic decarboxylati…on of its parent molecule, cannabidiolic acid (CBDA)…The data presented in this report suggest for the first time that as an active component in the cannabis plant, CBDA offers potential therapeutic modality in the abrogation of cancer cell migration, including aggressive breast cancers.”
http://www.ncbi.nlm.nih.gov/pubmed/22963825“Pathways mediating the effects of cannabidiol on the reduction of breast cancer cell proliferation, invasion, and metastasis. Our data demonstrate the efficacy of CBD in pre-clinical models of breast cancer. CBD inhibits human breast cancer cell proliferation and invasion. The results have the potential to lead to the development of novel non-toxic compounds for the treatment of breast cancer…”
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410650/“Cannabidiol Induces Programmed Cell Death in Breast Cancer Cells by Coordinating the Cross-talk between Apoptosis and Autophagy… In summary, we showed that CBD, a plant-derived cannabinoid, preferentially kills breast cancer cells…” http://mct.aacrjournals.org/content/10/7/1161.long
“Cannabis has been shown to kill cancer cells…” http://www.cancer.gov/cancertopics/pdq/cam/cannabis/patient/page1
“…cannabinoids may be able to kill cancer cells while protecting normal cells… A laboratory study of delta-9-THC… showed that it damaged or killed the cancer cells…A laboratory study of cannabidiol… showed that it caused cancer cell death…” http://www.cancer.gov/cancertopics/pdq/cam/cannabis/patient/page2
“Cannabinoids appear to kill tumor cells but do not effect their nontransformed counterparts and may even protect them from cell death.” http://www.cancer.gov/cancertopics/pdq/cam/cannabis/healthprofessional/page4
“Because cannabinoid receptors, unlike opioid receptors, are not located in the brainstem areas controlling respiration, lethal overdoses from Cannabis and cannabinoids do not occur.” http://www.cancer.gov/cancertopics/pdq/cam/cannabis/healthprofessional/page6
“…our studies have identified Id-1 as a critical regulator of breast cancer progression and suggest the feasibility of developing novel therapeutic approaches to target Id-1 expression to reduce breast cancer metastasis in humans.” http://www.pnas.org/content/100/23/13543
“Recent Research on Cannabinoids. We targeted breast cancer cells that expressed high amounts of the protein Id-1. CBD is highly effective at turning off this specific gene that controls breast cancer metastasis.” http://www.cpmc.org/professionals/research/programs/science/cannabidiolarticles.html
“Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells… CBD represents the first nontoxic exogenous agent that can significantly decrease Id-1 expression in metastatic breast cancer cells leading to the down-regulation of tumor aggressiveness…reducing Id-1 expression with cannabinoids could also provide a therapeutic strategy for the treatment of additional aggressive cancers because Id-1 expression was found to be up-regulated during the progression of almost all types…” http://mct.aacrjournals.org/content/6/11/2921.long
“Bay Area Researchers Claim Cannabis Can Cure Cancer” http://blogs.ocweekly.com/navelgazing/2013/04/bay_area_researchers_claim_can.php
“Cannabis oil stopped my cancer says Lake Macquarie’s Susannah Patch. A LAKE Macquarie woman whose ‘‘aggressive’’ breast cancer spread to various parts of her body including her spine and lungs credits her remarkable recovery to cannabis oil.” http://www.theherald.com.au/story/2587931/cannabis-oil-stopped-my-cancer/?cs=12
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