Cannabis Use in Patients with Fibromyalgia: Effect on Symptoms Relief and Health-Related Quality of Life

“We observe significant improvement of symptoms of FM in patients using cannabis… knowledge of the endocannabinoid system and the role of the stress system in the pathopysiology of FM suggest a new approach to the suffering of these patients… results together with previous evidence seem to confirm the beneficial effects of cannabinoids on FM symptoms.”

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3080871/?tool=pubmed

Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors

TRUTH: “Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors… nonpsychoactive cannabinoids can potentiate glycine receptors (GlyRs), an important target for nociceptive regulation at the spinal level… We report that systemic and intrathecal administration of cannabidiol (CBD), a major nonpsychoactive component of marijuana, and its modified derivatives significantly suppress chronic inflammatory and neuropathic pain without causing apparent analgesic tolerance… These cannabinoids may represent a novel class of therapeutic agents for the treatment of chronic pain and other diseases involving GlyR dysfunction.”

http://www.ncbi.nlm.nih.gov/pubmed/22585736