HIV/AIDS Cure May Be Found In Marijuana: Study

“It is even more evidence of our need for the government to stop punishing patients for using this relatively safe and non-toxic treatment method … ”

Curtis Rood,36, a Cohen House resident with limited mobility, smokes marijuana with the assistance of another resident on Sunday, Nov. 30,1997 in San Francisco. Cohen House provides an assisted living environment for individuals with the AIDS virus. Most of the residents use marijuana for its medicine benefits in alleviating nausua, pain, and helping to stimulate the appetite. Curtis' parrot and self proclaimed best friend, Kona, rests on his shoulder while in the backyard of Cohen House. (AP photo/Julie Stupsker)

“For years, many Americans with HIV/AIDS have used medical marijuana to relieve some common symptoms associated with the illness such as nausea, vomiting and appetite loss.

Now, a new study published last week in the journal AIDS Researcher and Human Retroviruses found that a daily dosage of marijuana’s psychoactive ingredient tetrahydrocannabinol, or THC, may actually fight the HIV/AIDS virus itself.”

More: http://www.mintpressnews.com/hivaids-cure-may-be-found-in-marijuana-study/179398/

HIV Infections Cured With Cannabis a Real Possibility

“Researchers are looking into the use of THC (tetrahydrocannabinol), the active ingredient in marijuana, to help stop the spread of HIV infection.

Hundreds of marijuana researchers have reported that THC was able to pierce the RIV virus in monkeys. That particular virus is almost identical to the HIV virus found in humans, so this news is very encouraging.

The greatest drawbacks to this excellent news are the current laws preventing testing on human candidates.

With the changing of these restrictive laws, HIV infections have a great chance of being cured, with cannabis as a real possible player in the race to stop the disease.”

More: http://guardianlv.com/2014/02/hiv-infections-cured-with-cannabis-a-real-possibility/

Weed cures AIDS according to a new study. YAY potheads

“According to a new study published in the journal PloS ONE, researchers from Mount Sinai School of Medicine discovered that marijuana-like compounds can inhibit the multiplication of human immunodeficiency virus (HIV) in late-stage AIDS by acting on viral receptors…

“We knew that cannabinoid drugs like marijuana can have a therapeutic effect in AIDS patients, but did not understand how they influence the spread of the virus itself. We wanted to explore cannabinoid receptors as a target for pharmaceutical interventions that treat the symptoms of late-stage AIDS and prevent further progression of the disease…”

More: http://www.gamespot.com/forums/offtopic-discussion-314159273/weed-cures-aids-according-to-a-new-study-yay-pothe-29105548/

 

HIV Cure: Medical Cannabis Or ‘Weed’ Explored To Help Stop HIV Infection Using THC Component; Laws Prevent Clinical Trials On Humans

“Medical cannabis is used as an appetite stimulant, antiemetic, antispasmodic and sometimes as analgesic to help treat chronic, non-cancerous pain, vomiting or nausea caused by chemotherapy. In some cases, it is also used to aid treating symptoms of AIDS patients…

Marijuana or “weed” is now among the several ingredients that researchers are looking into to helping stop further spread of HIV infection.”

More: http://au.ibtimes.com/articles/539079/20140217/hiv-cure-medical-cannabis-weed-explored-help.htm#.UxJCyPBX-uY

Breaking News: Study Says Marijuana May Stop the Spread of HIV

 

“People with HIV (and other conditions) have used prescription marijuana to treat the side effects of medication, but a new study published in the journal AIDS Research and Human Retroviruses, recently showed that daily doses of may even help combat the disease.”

More: http://www.hivplusmag.com/research/2014/02/11/breaking-news-study-says-marijuana-may-stop-spread-hiv

 

Marijuana as a possible treatment for HIV and cancer

Marijuana

“There’s been some interesting research on using THC (tetrahydrocannabinol), the principal psychoactive drug in marijuana, to help fight HIV, and damage cancer cells in some leukemias and possibly malignant tumors.

…the possibility exists that information from both of these research studies may produce beneficial results in the treatment of HIV and cancer.”

More: http://americablog.com/2014/02/marijuana-treatment-hiv-cancer.html

Weed Could Block H.I.V.’s Spread. No, Seriously.

“But the U.S. government won’t let scientists try out this promising treatment on humans… proving that an illegal drug can stop a deadly disease in humans—without testing it on them—is impossible…

THC is one of 500 active ingredients in marijuana. And marijuana, despite many studies proving its medical value, is sill classified by the government as a Schedule 1 Substance.

In the face of mounting evidence that it is beneficial in treating diseases… it remains a controlled substance.

During HIV infection, one of the earliest effects is that the virus spreads rapidly throughout the body and kills a significant part of cells in the gut and intestine. This activity damages the gut in a way that allows the HIV to leak through the cell wall of the intestines and into the bloodstream.

When THC is introduced into this environment, it activates the CB2 receptors in the intestines to build new, healthy bacterial cells that block the virus from leaking through the cell walls. In other words, the body works hard to keep bad stuff in the intestines and the good stuff out.

Put another way: HIV kills the cells that protect the walls— THC brings them back. Reducing the amount of the virus in the lower intestines could then help keep uninfected people uninfected.”

More: http://www.thedailybeast.com/articles/2014/02/15/weed-can-block-h-i-v-s-spread-no-seriously.html

Δ9-Tetrahydrocannabinol Treatment During Human Monocyte Differentiation Reduces Macrophage Susceptibility to HIV-1 Infection

“The major psychoactive component of marijuana, Δ9-tetrahydrocannabinol (THC), also acts to suppress inflammatory responses. Receptors for THC, CB1, CB2, and GPR55, are differentially expressed on multiple cell types including monocytes and macrophages, which are important modulators of inflammation in vivo and target cells for HIV-1 infection. Use of recreational and medicinal marijuana is increasing, but the consequences of marijuana exposure on HIV-1 infection are unclear. Ex vivo studies were designed to investigate effects on HIV-1 infection in macrophages exposed to THC during or following differentiation.

THC treatment of primary human monocytes during differentiation reduced HIV-1 infection…

THC treatment of monocytes during differentiation into MDMs suppresses HIV-1 infection. 
Ultimately, the mechanism of THC suppression of HIV-1 infection was traced to a reduction in cell surface HIV receptor (CD4, CCR5 and CXCR4) expression that diminished entry efficiency.”

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4019698/

Modulation of Gut-Specific Mechanisms by Chronic Δ9-THC Administration in Male Rhesus Macaques Infected with Simian Immunodeficiency Virus: A Systems Biology Analysis.

“Our studies have demonstrated that chronic Δ9-tetrahydrocannabinol (THC) administration results in a generalized attenuation of viral load and tissue inflammation in simian immunodeficiency virus (SIV)-infected male rhesus macaques…

Our results indicate that chronic THC treatment modulated duodenal T cell populations, favored a pro-Th2 cytokine balance, and decreased intestinal apoptosis.

These findings reveal novel mechanisms that may potentially contribute to cannabinoid-mediated disease modulation.”

http://www.ncbi.nlm.nih.gov/pubmed/24400995

“Previous studies from our laboratory have shown that chronic THC administration ameliorates SIV disease progression and significantly reduces the morbidity and mortality of male SIV-infected macaques… In summary, using a systems biology approach to understanding the impact of chronic cannabinoid treatment on gut-associated immunopathology, we identified relevant mechanisms that can potentially modulate disease progression. Our results suggest that gut immunomodulation through changes in gene expression, cytokine profiles, and immune cell populations could potentially contribute to chronic THC modulation of SIV disease progression. Moreover, they reveal novel mechanisms that may potentially contribute to decreased morbidity and mortality.”  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046212/