Category Archives: Post-Traumatic Stress Disorder (PTSD)

Cannabis News: The Cannabinoid System Reverses Dementia, Treats PTSD and Controls Diabetes Top May’s News Digest from Publius

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“The Cannabinoid System’s role in reversing dementia, treating PTSD and controlling diabetes highlight May’s cannabis news from Publius, the pen name used by the authors of The Cannabis Papers – Federal ignorance goes on unabated.”

“The Cannabinoid System’s (CS) role in reversing dementia, treating PTSD and controlling diabetes highlight May’s cannabis news from Publius, the pen name used by the authors of The Cannabis Papers: A citizen’s guide to cannabinoids (2011).”

More: http://www.prweb.com/releases/2013/5/prweb10787154.htm

Marijuana May Cure PTSD – NBC

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“Veterans suffering from post traumatic stress disorder may find help through marijuana.”

Cannabis Cup Cake Anyone?
  

“Could cannabis cure PTSD?

Post-traumatic stress disorder, which can also affect civilians who undergo a traumatic episode, may be cured by using marijuana, according to an East Bay Express report.

A researcher at Yale University is conducting a long-term study with 120 people — veterans with “intractable cases of PTSD” — who he thinks can be cured of their dehabilitating condition with marijuana.

Most people suffering from PTSD go through a regimen of drugs or more-invasive “exposure therapy,” in which they dig as deeply as possible into their trauma for 12 weeks. Most drop out in Week 3, according to the report.

The theory of R. Andrew Sewell is that tetrahydrocannabinol, or THC, one of the active ingredients in cannabis, can help the brain learn new information. This in turn helps people suffering from PTSD forget the old — as in bad — information.

This is called “extinction learning,” Sewell says. And such learning is made easier when a “switch” in the brain called CB1 is activated. It turns out cannabis is very good at activating the CB1 receptor.

“We’re talking about a cure,” said Sewell, who noted that after treatment, no drugs — not cannabis and not antidepressants — would be required.”

http://www.nbcbayarea.com/news/local/Marijuana-May-Cure-PTSD-208900021.html 

Marijuana May Help Cure PTSD

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“A Yale associate professor of psychiatry is giving American veterans with intractable post traumatic stress disorder the main active ingredient in marijuana as part of search for a better PTSD cure.”

“Former chief resident in neuropsychiatry at the University of Massachusetts School of Medicine R. Andrew Sewell said PTSD and other anxiety disorders might hinge on a defect in brain cells that the marijuana molecule, “THC”, can help alleviate.

In addition to being part of a potential cure, marijuana (aka cannabis) is already being used for PTSD symptom management by thousands of veterans, said MAPS scientist Dr. Sue Sisley.

“Veterans use cannabis for two reasons, one it makes them less irritable, which is really socially destructive and also it helps them sleep. Cannabis is excellent for sleep, it is much better than alcohol.”

Still, the U.S. government maintains a research blockade on the 10,000 year-old medicinal botanical. For example, the D.E.A. has blocked MAPS from carrying out an FDA-approved study of smoked cannabis on veterans with PTSD.”

More: http://blog.sfgate.com/smellthetruth/2013/05/23/marijuana-may-help-cure-ptsd/

The endocannabinoid system and its therapeutic exploitation.

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“The term ‘endocannabinoid’ – originally coined in the mid-1990s after the discovery of membrane receptors for the psychoactive principle in Cannabis, Delta9-tetrahydrocannabinol and their endogenous ligands – now indicates a whole signalling system that comprises cannabinoid receptors, endogenous ligands and enzymes for ligand biosynthesis and inactivation. This system seems to be involved in an ever-increasing number of pathological conditions. With novel products already being aimed at the pharmaceutical market little more than a decade since the discovery of cannabinoid receptors, the endocannabinoid system seems to hold even more promise for the future development of therapeutic drugs. We explore the conditions under which the potential of targeting the endocannabinoid system might be realized in the years to come.”  http://www.ncbi.nlm.nih.gov/pubmed/15340387

http://www.nature.com/nrd/journal/v3/n9/full/nrd1495.html

Marijuana Can Help Prevent Suicide, Study Suggests

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“Marijuana does many magical things, not the least of which is make dubstep listenable. In Los Angeles, we use it pretty much legally for back pain, nausea and hot tubbing.

But a new study from Germany says that, in U.S. states like California where marijuana has become medically legit, rates of suicide have gone down.

The researchers note that suicide is often triggered by “stressful life events.” And you know what can take away the pain?

No. Not Enrique Iglesias. Stress! Or rather, chronic. Depending.

The academics note that “California includes anxiety as a qualifying condition” to obtain medical pot, “while Delaware and New Mexico both allow the use of medical marijuana for post traumatic stress disorder … ”

The Institute for the Study of Labor (IZA) in Bonn, with the help of American researchers such as Daniel I. Rees of the University of Colorado’s Department of Economics, recently published their findings in a paper called High on Life? Medical Marijuana Laws and Suicide (PDF):

Our results suggest that the passage of a medical marijuana law is associated with an almost 5 percent reduction in the total suicide rate, an 11 percent reduction in the suicide rate of 20- through 29-year-old males, and a 9 percent reduction in the suicide rate of 30- through 39-year-old males.

The study takes some wild guesses, and one of them is that maybe medical marijuana users are cutting out the alcohol, which can be depressive:

The strong association between alcohol consumption and suicide related outcomes found by previous researchers (Markowitz et al. 2003; Carpenter 2004; Sullivan et al. 2004; Rodriguez Andres 2005; Carpenter and Dobkin 2009) raises the possibility that medical marijuana laws reduce the risk of suicide by decreasing alcohol consumption.

The academics cite research on animals where there was “a potent anti-depressant effect” when they were injected with low doses of synthetic cannabinoid.

Of course this flies in the face of tons of research — not to mention what Dr. Drew Pinsky has said several times — that cannabis and depression go together like milk and cookies.

And, it seems clear to us, the only solid argument to be made here is there might be a correlation between medical marijuana states and lower rates of suicides.

Hmm. National suicide rates have been decreasing across the board.

Researchers say they focused mostly on young men because most medical marijuana patients in states like Arizona, Colorado and Montana are males, and roughly half are under 40. Data on women, apparently, was weak. (Women are four times less likely to commit successful suicide in general).

The German study’s rosy conclusion:

… The legalization of medical marijuana leads to an improvement in the psychological well being of young adult males, an improvement that is reflected in fewer suicides.

Believe that. Or not.”

By Dennis Romero

http://blogs.laweekly.com/informer/2012/02/marijuana_suicide_medical_states_california.php

Marijuana Prevents Suicides

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“In 2010, 38 thousand people committed suicide. About seven thousand were veterans.”

PTSD: U.S. soldier on patrol in Kabul
“U.S. soldier on patrol in Kabul – by Tim King Salem-News.com

(PORTLAND, OR) – The Oregonian and and The New York Times both had headlines, May 3, 2013, ‘Suicides Surge in United States and Oregon’.

I believe military PTSD victims have the highest rate but there are far more civilians in that same age group. For veterans, it is about 20 suicides per day, what that amounts to per thousand patients is the different kind of statistic that I am familiar with. The newspaper articles give their statistics as so many per thousand. They indicate that currently, the suicide rate for the middle aged, (35-64) is 18 per thousand each year, that age group is the highest rate. The overall rate for the U.S. is 14 per thousand per year.

I know more about the military veterans because I had more than 1,000 in my total population of 5,000 patients. Considering that the military veterans represent only about 1% of the population, with my 20% being veterans, this makes a good study group.

For military veterans, PTSD, from mild to severe, is about 20% of the group. This means 600 thousand PTSD victims. The actual figure is probably higher. Most are not being treated by the VA and they are using a number of different therapies. Many who live in states where it is legal, have reverted to marijuana. But many states, including Oregon, will not accept PTSD for a permit. New Mexico does allow Marijuana for PTSD Veterans. In New Mexico, 50% of the permit holders are veterans.

I started seeing military PTSD veterans about as soon as Oregon’s medical marijuana law became effective. But PTSD is not acceptable in Oregon. Most veterans had physical wounds, making them eligible for a permit.

I wrote my first article on this subject, February 13, 2009, ‘Marijuana Vs Antidepressants for PTSD’. The VA uses these drugs by the ton and while deadly, they are no more effective than sugar pills, but usually worse and often are used for suicide. That article has had 868 Facebook recommends, indicating strong interest.

My second article, ‘Medical Marijuana Prevents PTSD Suicides!’, was published Sept 22 2012., has 581 FB recommends.

My latest article on this subject, from March 25 2013, ‘PTSD/Depression and Anguish: Marijuana Vs. Many Fake Dangerous Drugs’ had 340 recommends.

This gets us to the current newspaper articles, in which military suicides are not even mentioned!

When you are 50, looking for a job, it can be fruitless. And it must be getting as bad for those even in their 40’s because the bright young smart alecks are striving to get into the workplace before it is too late.

The unemployed are now in desperate situations with no good way out and no resources. Anguish overtakes them and depression may be one of the symptoms for PTSD, etc.

There are about 19 states with legal marijuana, which represents more than 50% of the U.S. population. And speaking of those 19 states, those people can use this valuable medicine, marijuana. Another option is alcoholism and death.”

 

“MEDICAL MARIJUANA IS THE BEST ANTI-SUICIDE DRUG!”

-Dr. Phillip Leveque Doctor of Pharmacology Salem-News.com

http://salem-news.com/articles/may032013/ptsd-suicides-pl.php

Marijuana-like compound could lead to first-ever medication for PTSD – Fox News

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“The life of an individual suffering from post-traumatic stress disorder (PTSD) is often a debilitating one, as patients are frequently plagued by intense nightmares, flashbacks and emotional instability.   

There are a number of psychotherapeutic treatments and cognitive behavioral therapy options to aid sufferers of PTSD, but these interventions are not always available to patients.  And while medications tend to be the first line of defense for these individuals, no pharmaceutical treatments have been developed yet to specifically target PTSD.

But now, new research may help dramatically change the course of treatment for PTSD patients.  In the first study of its kind, researchers at New York University Langone Medical Center have utilized brain imaging technology to highlight a connection between the number of cannabinoid receptors in the brain and PTSD.  Cannabinoid receptors, known as CB1 receptors, are activated in the brain when a person uses cannabis, which can lead to impaired memory and reduced anxiety.

The researchers’ findings pave the way for the development of the first every medication designed explicitly to treat trauma – something, they say, is desperately needed.”

Read more: http://www.foxnews.com/health/2013/05/14/marijuana-like-compound-could-lead-to-first-ever-medication-for-ptsd/#ixzz2TN3QNhPO

Brain-Imaging Study Links Cannabinoid Receptors to Post-Traumatic Stress Disorder: First Pharmaceutical Treatment for PTSD Within Reach

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“In a first-of-its-kind effort to illuminate the biochemical impact of trauma, researchers at NYU Langone Medical Center have discovered a connection between the quantity of cannabinoid receptors in the human brain, known as CB1 receptors, and post-traumatic stress disorder, the chronic, disabling condition that can plague trauma victims with flashbacks, nightmares and emotional instability…

CB1 receptors are part of the endocannabinoid system, a diffuse network of chemicals and signaling pathways in the body that plays a role in memory formation, appetite, pain tolerance and mood. Animal studies have shown that psychoactive chemicals such as cannabis, along with certain neurotransmitters produced naturally in the body, can impair memory and reduce anxiety when they activate CB1 receptors in the brain…

“There’s not a single pharmacological treatment out there that has been developed specifically for PTSD,” says Dr. Neumeister. “That’s a problem. There’s a consensus among clinicians that existing pharmaceutical treatments such as antidepressant simple do not work. In fact, we know very well that people with PTSD who use marijuana — a potent cannabinoid — often experience more relief from their symptoms than they do from antidepressants and other psychiatric medications. Clearly, there’s a very urgent need to develop novel evidence-based treatments for PTSD.”

Read more: http://www.sciencedaily.com/releases/2013/05/130514085016.htm

Elevated brain cannabinoid CB1 receptor availability in post-traumatic stress disorder: a positron emission tomography study.

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“Endocannabinoids and their attending cannabinoid type 1 (CB1) receptor have been implicated in animal models of post-traumatic stress disorder (PTSD)…

These results suggest that abnormal CB1 receptor-mediated anandamide signaling is implicated in the etiology of PTSD, and provide a promising neurobiological model to develop novel, evidence-based pharmacotherapies for this disorder.”

http://www.ncbi.nlm.nih.gov/pubmed/23670490

Medical cannabis relieves sufferers of chronic ailments

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“Treatment can improve appetite, ease chronic pain, and more, say TAU researchers. Though controversial, medical cannabis has been gaining ground as a valid therapy, offering relief to suffers of diseases such as cancer, Post-Traumatic Stress Disorder, ALS and more. The substance is known to soothe severe pain, increase the appetite, and ease insomnia where other common medications fail.”

More: http://www.virtualmedicalcentre.com/news/medical-cannabis-relieves-sufferers-of-chronic-ailments/18330