“Cannabidiol (CBD), a major non-psychotomimetic constituent of Cannabis sativa with anti-inflammatory and neuroprotective properties induces antipsychotic-like effects.
The present study evaluated if repeated treatment with CBD would attenuate the behavioral and glial changes observed in an animal model of schizophrenia…
These data reinforces the proposal that CBD may induce antipsychotic-like effects.
Although the possible mechanism of action of these effects is still unknown, it may involve CBD anti-inflammatory and neuroprotective properties.
Furthermore, our data support the view that inhibition of microglial activation may improve schizophrenia symptoms.”