“To analyze motivation, food self-administration and decision-making was evaluated in adolescent, adult and aged rats.
Adolescent rats exhibited low expression of CB1R in the NAcc and low expression of both CB1R and CB2R in the PFC compared to adult and aged rats.
Adolescent rats display higher motivation for palatable food and an indiscriminate seeking behavior suggesting involvement of both homeostatic and hedonic systems in their decision-making processes.”