“Cannabidiol (CBD) has anti-inflammatory effects.
We explored its therapeutic effects on cardiac ischemia-reperfusion injury with an experimental imaging platform…
Compared to controls, CBD treatment improved systolic wall thickening, significantly increased blood flow in the AAR, significantly decreased microvascular obstruction, increased the PDR by 1.7-fold, lowered the AMI-core/AAR ratio, and increased the MSI.
These improvements were associated with reductions in serum cTnI, cardiac leukocyte infiltration, and myocellular apoptosis.
Thus, CBD therapy reduced AMI size and facilitated restoration of LV function.
We demonstrated that this experimental platform has potential theragnostic utility.”