“The levels of the endocannabinoids anandamide (AEA) and 2-arachidonoylglycerol.
In this study, we investigated the role of the endocannabinoid system (ECS) in the emotional and cognitive alterations associated with osteoarthritis pain.
Changes found in these biomarkers of the ECS correlated with pain, affective and cognitive symptoms in these patients.
The ECS plays a crucial role in osteoarthritis and represents an interesting pharmacological target and biomarker of this disease.”