Safety, pharmacodynamics, and pharmacokinetics of multiple oral doses of delta-9-tetrahydrocannabinol in older persons with dementia

“In this randomized, double-blind, placebo-controlled, crossover trial, we evaluated the safety, pharmacodynamics, and pharmacokinetics of THC…

Older people with dementia and physical comorbidity could greatly benefit from the therapeutic application of cannabinoids. Recent studies have demonstrated that low doses of THC are effective in protecting the brain from neuroinflammation-induced cognitive damage.

Our findings suggest that low THC doses are safe and well tolerated by frail older persons with dementia.”

http://link.springer.com/article/10.1007/s00213-015-3889-y

“Our findings suggest that low THC doses are safe and well tolerated by frail older persons with dementia.” http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480847/

 

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