Sex-dependent effects of cannabis-induced analgesia.

“Preclinical studies demonstrate that cannabinoid-mediated antinociceptive effects vary according to sex; it is unknown if these findings extend to humans.

These results indicate that in cannabis smokers, men exhibit greater cannabis-induced analgesia relative to women.

As such, sex-dependent differences in cannabis’s analgesic effects are an important consideration that warrants further investigation when considering the potential therapeutic effects of cannabinoids for pain relief.”

http://www.ncbi.nlm.nih.gov/pubmed/27522535

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