Stoners aren’t known for their memory prowess but a new review suggests that drugs similar to marijuana’s active ingredients may hold promise for preventing— or even reversing— brain aging and possibly Alzheimer‘s and other degenerative brain diseases.
Read more: http://healthland.time.com/2012/10/29/how-cannabinoids-may-slow-brain-aging/#ixzz2AjCxutuI
“CBD is able to modulate microglial cell function in vitro and induce beneficial effects in an in vivo model of AD. Given that CBD lacks psychoactivity, it may represent a novel therapeutic approach for this neurological disease.”
http://www.medicalmarijuanainc.com/index.php/alzheimer-s-disease
“Our results indicate that cannabidiol exerts a combination of neuroprotective, anti-oxidative and anti-apoptotic effects against beta-amyloid peptide toxicity, and that inhibition of caspase 3 appearance from its inactive precursor, pro-caspase 3, by cannabidiol is involved in the signalling pathway for this neuroprotection.”
“Our results indicate that cannabinoid receptors are important in the pathology of AD and that cannabinoids succeed in preventing the neurodegenerative process occurring in the disease.”
“the investigators confirmed that cannabinoids counteracted the activation of microglia and thus reduced inflammation. These findings that cannabinoids work both to prevent inflammation and to protect the brain may set the stage for their use as a therapeutic approach for Alzheimer’s disease, de Ceballos said.”