The association of N-palmitoylethanolamine with the FAAH inhibitor URB597 impairs melanoma growth through a supra-additive action.

“The incidence of melanoma is considerably increasing worldwide. Frequent failing of classical treatments led to development of novel therapeutic strategies aiming at managing advanced forms of this skin cancer. Additionally, the implication of the endocannabinoid system in malignancy is actively investigated…

CONCLUSIONS:

This study suggests the interest of targeting the endocannabinoid system in the management of skin cancer and underlines the advantage of associating endocannabinoids with enzymatic hydrolysis inhibitors.

This may contribute to the improvement of long-term palliation or cure of melanoma.”

Full text: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364151/

The trypanocidal effect of Cannabis sativa constituents in experimental animal trypanosomiasis.

Image result for cannabis sativa

“The effect of Cannabis sativa on trypanosome-infected rats was examined. An aqueous extract of the seeds administered at a dose of 50 mg/kg/d cured animals infected with Trypanosome brucei brucei of blood stream parasites.

Six fractions eluted from the crude extract by column chromatography were assessed for trypanocidal properties. Of these, only 2 fractions retained trypanocidal activity by curing mice infected with T brucei brucei.”

http://www.ncbi.nlm.nih.gov/pubmed/7900270

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“Trypanosoma brucei is a species of parasitic kinetoplastid belonging to the genus Trypanosoma. The parasite is the cause of a vector-borne disease of vertebrate animals, including humans, carried by genera of tsetse fly in sub-Saharan Africa. In humans T. brucei causes African trypanosomiasis, or sleeping sickness.”  https://en.wikipedia.org/wiki/Trypanosoma_brucei

“A trypanocidal agent is an antiprotozoal agent that acts upon trypanosome parasites.”  https://en.wikipedia.org/wiki/Trypanocidal_agent

Cannabis/Marijuana: A Parkinson’s Cure

“This is a pretty raw video, but we think it shows better than any scientific article the powerful healing nature of Cannabis.  How can you beat a medicine that can be grown and prepared at virtually no cost, that not only has no side effects, but instead leaves you happy?

In this video, a man suffering from Parkinson’s takes a puff of Cannabis at about 2 minutes.  By 6 minutes into the video, he is no longer shaking, but laughing!  They also speak of *hemp oil, which is the most potent form of medical marijuana.

People with Parkinsons and other neurological disorders are often prescribed a myriad of strong pharmaceutical medications that can produce horrendous side effects….. side effects are not small issues.  They usually  require additional medication.  After a while, the liver and kidneys can become irrevocably damaged. As for the safety of the pharmaceutical medicines, we recommend this video: Marijuana is EXTREMELY dangerous.”

http://patients4medicalmarijuana.wordpress.com/2009/09/22/cannabismarijuana-a-parkinsons-cure/

Cannabis linked to ‘prostate cancer cure’

“Cannabis helps combat prostate cancer, scientists revealed yesterday.

But patients were warned not to use the drug even though active chemicals halted the spread of the disease.

Cannabis also helped reduce the size of tumours when tested on mice, according to researchers at Spain’s University of Alcala.

But Cancer Research UK’s Dr Lesley Walker said: “This opens a new avenue to explore potential drug targets but it is at a very early stage – it absolutely isn’t the case that men might be able to fight prostate cancer by smoking cannabis.

“Research suggests that prostate cancer cells might stop growing if they are treated with chemicals found in cannabis but more work needs to be done to explore the potential of these cannabinoids in treatment.”

Prostate cancer affects more than 35,000 UK men each year and kills around 10,000.”

http://www.mirror.co.uk/news/uk-news/cannabis-linked-to-prostate-cancer-cure-413459

Cannabis Cures Cancer

“I’m a cancer patient. I use an experimental chemotherapy that is an extraction of the cannabis plant. I don’t use it to feel good. I use it for the purpose of killing the cancer.

Right now, there are about fifty people making this experimental chemotherapy in the state of Michigan. As a result of the opinion issued by the attorney general, the number of people willing to create this substance may now be reduced to two or three. All are working at a fevered pace trying to keep patients alive. The clock is ticking. Most of the time we have one single chance to get it right. Most of the patients we deal with will die before we get a second try.

It takes about one pound of the highest quality cannabis flowers to make enough of this extract for one single procedure, for one single patient. This extract is eaten by the patient within sixty to 90 days. This is a much higher dose that normally used to get “high.”

The procedure cannot be stopped and restarted. It is used in a way that is similar to antibiotics. You can’t stop and start antibiotics. If you do, the infection gets stronger and more difficult to get rid of. The same seems to hold true for cancer. You simply can’t play the hit and miss game with cancer. If you are on target, it MUST be completed. What is required, to stay alive, is an uninterrupted supply of the medicine. Enough to last through the entire 90 day procedure.

It is very difficult to find enough material for a single patient. Within the community we have been begging for scraps for the last two years. Begging over and over again just to supply the needs for one single patient. So we work with left over trimmings that normally would have been burned or buried. Material that no one would want. Thieves that break into our growing areas would ignore the scrap. They view it as worthless.

This useless material has had negative impact on many court cases in this state. By law, if you forget to burn some scrap, it gets counted toward the limit of 2.5 ounces. Most of us are attempting to avoid that extra scrap excess. We burn and bury any hint of excess material as quickly as possible. If we’re caught trying to do so it could well mean a felony conviction. If we delay by just a few hours we could be arrested and convicted.

Those that have been already growing marijuana and receive fresh news that they have cancer are the lucky ones. The just might have the material needed to stay alive. Might. It depends on if they have been successful in growing, if they’ve avoided fungus and insect attacks long enough to produce usable material. If they’ve learned the right nutrient combinations to apply to their indoor growing plants that afford the maximum yield.

If the patient has luck after luck, they are then at a place they can attempt to make this extract for themselves.

For a very long time, there have been many studies that show the compounds in cannabis kill cancer cells. These studies first started reporting this effect in 1974. Hundreds, if not thousands, of such scientific studies have been published but our government and most other governments of the world have refused to allow testing in humans, with very few exceptions.  Only one or two such studies have been allowed. Not one single human study has been allowed in the US in the last seventy years. Without human testing, our government relies on the statement “this hasn’t been proven in human testing,” which is technically correct because such testing isn’t allowed.

The voters of Michigan have told the government that it is acceptable to use this plant for medical purposes. It’s time for those officials to obey the voters.

While it is a noble thing to decrease the suffering of someone that is dying, I would rather see these same people survive. Wouldn’t you?

Gersh Avery is Cofounder of the Cannabis Cancer Project. He lives in Dexter.”

http://themidwestcultivator.com/marijuana-news-editorial/02-2012/cannabis-cures-cancer

The NFL’s Campaign Against Breast Cancer Is a Total Scam

 

The NFL's Campaign Against Breast Cancer Is a Total Scam“Have you noticed that during the month of October, the NFL suddenly becomes intensely concerned with making sure you’re aware of breast cancer? Pink jerseys! Huge Ass Pink Ribbons at midfield! Pink motherfucking cleats! Fans interested in aware-ing on their own can even click on over to the NFL’s store and purchase ugly pink crap of their own under the assumption that their good intentions will actually contribute to the fight against cancer. Well, I hate to burst your Pepto Bismo Pink bubble, wearers of dangly earrings that contain both ribbons and tiny footballs, but you’ve been had — the NFL’s Breast Cancer Awareness Month campaign does raise itsy bitsy amounts of money for the fight against cancer, but the amount of money it raises pales in comparison to the amount of money it raises for billionaire NFL owners.

The NFL claims that its pink philanthropy efforts “support the fight against breast cancer” by “promoting awareness” and providing funds to the American Cancer Society. But what they’re mostly promoting is, uh, buying NFL gear, the profits from which are overwhelmingly pocketed by the NFL.

According to Business Insider, the NFL’s October Breast Cancer Awareness Month fundraising effort is multi-pronged. There’s the on-field onslaught of pink (AWARENESS), the off-field auction of autographed or otherwise noteworthy NFL paraphernalia (MONEY FOR THE CURE!), and the part of the NFL store that entices shoppers to purchase officially licensed NFL breast cancer gear, a portion of which goes to FINDING A CURE. According to the League, 100% of the proceeds from the specialty auction go to the American Cancer Society, but the total percentage of purchases of officially licensed gear that actually goes to FINDING A CURE is actually kind of pathetic — 5%. If you want to look at this cynically, in a way, the on-field wearin’ o’ the pink serves as an ad to direct consumers to purchase pink fan items.

BUT WAIT, you might say, AT LEAST THEY’RE DOING SOMETHING. And 5% is still something! Well, kind of. As BI pointed out, if NFL products are sold at a 100% markup and only 5% of sale proceeds go to the American Cancer Society, then the NFL is pocketing 90% of sales of Breast Cancer Awareness products, many of which would not be purchased if they didn’t come with a promise that consumers were “helping.” And, more perspective: while the American Cancer Society isn’t, say, Komen, they still don’t use 100% of the money they receive to “fight” breast cancer. Only 70% of donations taken in by the organization go toward cancer research. So, if you spend $10 on pink stink from the NFL, only about 35 cents is going to finding a cure for breast cancer. And $4.50 goes right back to the NFL, where I like to imagine that it’s spent on gas for a Lake Minnetonka pleasure cruise. For the cure.

But what about awareness?! Surely the NFL is helping keep people aware and alert and vigilant that at any moment, breast cancer could be lurking around a corner in a dark alley waiting with a hot pink switchblade to steal your purse and boobs. The thing about awareness is that it’s all but impossible to quantify — and everyone knows about breast cancer. If you asked 100 people if they’re aware that breast cancer is a thing and that it’s almost impossible to predict and most often affects women, I’d bet that most of them would nod before slowly backing away from you. Breast cancer awareness is so ubiquitous that if deadly diseases attended the same high school, breast cancer would probably be voted prom queen. The “awareness” that comes from the NFL’s sales of pink branded items doesn’t justify the extent to which the league is taking advantage of consumers’ good intentions to pad their wallets. Even if no NFL player ever touched another pink thing again, Americans would go right on being aware of the disease. Unless the Buffalo Jills or New Orleans Saintsations cheerleaders are holding up signs that show women how to give themselves breast self-exams or tickets come with 5 page printouts of places low income women can obtain breast health screening for low or no cost, the type of awareness the NFL is providing is useless, vague garbage.

Since the program’s inception four years ago, the NFL has raised $3 million for breast cancer. In 2009, the League made $8.5 billion. Last year, they made $9.5 billion. Commissioner Roger Goodell has set a revenue goal of $25 billion per year by the year 2027. A million per year out of between $8.5 and $9.5 billion in revenues? Pardon me while I don’t slobber all over the NFL’s pink-drenched marketing campaign.

Want to cure breast cancer? Give directly to an organization that cures breast cancer, or to an advocacy group that seeks actual cures, not marketing and corporate profits. Besides, wearing those horrid pink NFL breast cancer rain boots actually causes cancer. Of the eyes.”

http://jezebel.com/5950971/the-nfls-campaign-against-breast-cancer-is-a-total-scam

Is the pink ribbon campaign a scam?

“The pink ribbon has become synonymous with solidarity for women who battle breast cancer. After all, a diagnosis of breast cancer changes the life of the diagnosed and the lives of all those involved — many times for the worse.

But, did you ever stop to think about what the pink ribbon campaign is all about? Is it really meant to bring “awareness” to breast cancer? Hasn’t everyone heard of breast cancer? Some have questioned the motives of those who stand behind those pretty pink ribbons.

Some have suggested that Breast Cancer Awareness month can be seen as a push for women to be corralled into the mammography suite so they can await their breast cancer diagnosis when the mammography is complete.

The science behind mammography is clear. Mammography does more harm than good.

Yes, the concept seems harsh. After all, most people who wear pink ribbons are innocent. They just go along with the rest. It’s a chance to show that they support the cause, whatever that is.

The pink ribbon campaign, however, is not completely innocent. Take for example this questionable involvement in the pink ribbon campaign. In October 2010, KFC filled and sold the “Bucket for the Cure,” donating 50 cents to breast cancer for each bucket sold. If KFC had a real interest for preventing breast cancer or for finding its cure, wouldn’t they close their doors forever? After all, the Physicians Committee for Responsible Medicine (PCRM) sued KFC for not disclosing to its customers that the chicken sold at KFC contained a dangerous carcinogen. “KFC should post warnings because its aggressively marketed new product harbors a chemical that increases the risk of breast cancer, prostate cancer, and other forms of this lethal disease,” commented Dr. Neal Barnard, of PCRM.

While some participants in the pink ribbon campaign do send raised funds to breast cancer charities, such as Komen for the Cure, others do not follow through with contributions. The Better Business Bureau has issued warnings to consumers regarding this shell game.

Pink Ribbons have hope. On the other hand, the entire breast cancer awareness initiative would be worthwhile if we continued to raise money to advertise the information that we already have about breast cancer prevention: diet, exercise, stress management prevent breast cancer. Why is it that people do not know that eating a low-fat whole plant foods diet is the single most important thing you can do to prevent breast cancer? Why don’t breast cancer organizations teach what we already know instead of continuing to look for a cure that comes in an expensive pill, treatment, or surgery?

Who’s benefiting here, anyway?”

Marijuana: A cure for breast cancer

“Cannabis, or rather marijuana, has been known as an illegal drug that is used primarily to get “high” and has no other value. This is what many people have thought of marijuana for at least the last 75 years.

Over the years, numerous research studies have been conducted on cannabis and there were discussions about its medicinal benefits for cancer treatment; however, because this is an illegal drug, much of the research hasn’t been known to the average citizen.

Within the last 10-15 years, the interest in cannabis as a possible cure for cancer has increased substantially. In addition, there has been an increase in citizens demanding the ability to use medicinal cannabis as a treatment for their disease or illness.

These recent studies have shown that cannabis may be a cure for cancer.  One study
conducted in 2007 by the California Pacific Medical Center in San Francisco, CA determined that a compound in cannabis called “Cannabidiol” was effective at inhibiting aggressive breast cancers. It was discovered that a certain “key gene caused breast cancer to spread and that cannabidiol could inhibit that aggressive gene by stopping the spread of the tumor cells”.  This study was published in the Washington Post and Science Daily
as well.

Unfortunately, cannabis is a schedule 1 drug which means that additional research and FDA approval would be required for cannabis to be used for the treatment of cancer.  It would require the removal of cannabis as a schedule 1 drug.

There is information that may suggest the U.S. Government and the Drug Enforcement Agency (DEA) may have already known about the benefits of cannabis to treat cancer. The National Cancer Institute published a study in 1974. Due to federal law, no further studies were conducted until the 1990’s. All research conducted since then has been via test tube and animal studies.

In an October 2003 review on test tube and animal research indicated that cannabinoids inhibit tumors of the lung, uterus, skin, breast, prostate, and brain. Cannabis is also known to provide nausea relief to cancer patients and to increase appetite.

Medicinal cannabis may be the cure for cancer. Additional research is needed; however, it may require reclassifying cannabis in order to obtain government approval.”

http://www.examiner.com/article/marijuana-a-cure-for-breast-cancer

Rimonabant: an antagonist drug of the endocannabinoid system for the treatment of obesity.

Abstract

“Obesity, an ever-increasing problem in the industrialized world, has long been a target of research for a cure or, at least, control of its expansion. In the search for treatment, the recently discovered endocannabinoid system has emerged as a new target for controlling obesity and its associated conditions. The endocannabinoid system plays an important role in controlling weight and energy balance in humans. This system is activated to a greater extent in obese patients, and the specific blockage of its receptors is the aim of rimonabant, one of the most recent drugs created for the treatment of obesity. This drug acts as a blockade for endocannabinoid receptors found in the brain and peripheral organs that play an important role on carbohydrate and fat metabolism. Clinical studies have confirmed that, when used in combination with a low calorie diet, rimonabant promotes loss in body weight, loss in abdominal circumference, and improvements in dyslipidemia. Rimonabant is also being tested as a potential anti-smoking treatment since endocannabinoids are related to the pleasurable effect of nicotine. Thus, rimonabant constitutes a new therapeutic approach to obesity and cardiovascular risk factors. Studies show effectiveness in weight loss; however, side effects such as psychiatric alterations have been reported, including depression and anxiety. These side effects have led the FDA (Food and Drug Administration) to not approve this drug in the United States. For a more complete evaluation on the safety of this drug, additional studies are in progress.”

http://www.ncbi.nlm.nih.gov/pubmed/19443932

Cannabis Science Announces Critical Cancer Patient Dr. Lynnice Wedewer, Ph.D., Cured Seven Times By Medical Cannabis

“Cannabis Science Inc. a pioneering US biotech company developing pharmaceutical cannabis products, is pleased to announce that it has been contacted by Lynnice Wedewer, Ph.D. who is a 34 year multiple cancer patient survivor who has been cured of 7 of her 8 cancers in a major part because of medical cannabis.

Dr. Wedewer wishes to share her story through Cannabis Science and help our case and education towards general acceptance of medical cannabis as a natural and viable treatment for cancer.”

 More: http://www.reuters.com/article/2011/06/29/idUS207485+29-Jun-2011+BW20110629