“Studies have shown that cannabinoid CB2 receptors are involved in wound repair, however, its physiological roles in fibrogenesis remain to be elucidated.
In the present study, the capacity of cannabinoid CB2 receptors in the regulation of skin fibrogenesis during skin wound healing was investigated.
These results indicated that cannabinoid CB2 receptors modulate fibrogenesis and the TGF‑β/Smad profibrotic signaling pathway during skin wound repair in the mouse.”
“An immunomodulatory role for the endocannabinoid system in gastrointestinal inflammatory disorders has been proposed and this study sought to determine the location of both cannabinoid receptors in human colon and to investigate epithelial receptor function.
Cannabinoids enhanced epithelial wound closure…
CB1 receptors are expressed in normal human colon and colonic epithelium is responsive biochemically and functionally to cannabinoids. Increased epithelial CB2-receptor expression in human inflammatory bowel disease tissue implies an immunomodulatory role that may impact on mucosal immunity.”
“Dynamic localization of CB2R and quantitative analysis of CB2R mRNA during skin wound healing in mice were performed…
In conclusion, dynamic distribution and expression of CB2R suggest that CB2R is involved in modulating macrophages and myofibroblasts in response to inflammatory event and repair process in mouse skin wound healing, and CB2R is available as a marker for wound age determination.”
“The expression of the cannabinoid receptor type 2 (CB2R) was investigated by immunohistochemistry, Western blotting, and RT-PCR during wound healing of contused skeletal muscle in rats with attempt of its applicability to skeletal muscle wound age estimation…
In conclusion, dynamic distribution and expression of CB2R suggest that CB2R be involved in modulating macrophages in response to inflammatory event in rat skeletal muscle wound healing and CB2R be available as a marker for wound age determination.”
“To investigate the expression of cannabinoid receptor I (CB1R) during mice skin incised wound healing course and time-dependent changes of CB1R in wound age determination…
The control group showed a low expression of CB1R detected mainly in epidermis, hair follicles, sebaceous gland and dermomuscular layer. CB1R expression was undetectable in neutrophils in the wound specimens from 6h to 12h post-injury.
The positive bands of CB1R were observed in all time points of the wound healing course…
CB1R is activated during the wound healing course. The expression of CB1R is found in mononuclear cells, which could be involved in inflammation reaction. CBIR is observed in fibroblastic cells, which could participate in the wound healing. CB1R may be a potentially useful marker for determination of wound healing age.”
“Cannabinoid ligands regulate bone mass, but skeletal effects of cannabis (marijuana and hashish) have not been reported. Bone fractures are highly prevalent, involving prolonged immobilization and discomfort.
Here we report that the major non-psychoactive cannabis constituent, cannabidiol (CBD), enhances the biomechanical properties of healing rat mid-femoral fractures.
Using Fourier Transform Infrared Spectroscopy we confirmed the increase in collagen crosslink ratio by CBD, which is likely to contribute to the improved biomechanical properties of the fracture callus.
Taken together, these data show that CBD leads to improvement in fracture healing and demonstrate the critical mechanical role of collagen crosslinking enzymes.”
“CBD-only laws are a pretext to extend marijuana prohibition under the guise of ‘protecting the children.'”
“Ever since marijuana was banned by the federal government in the 1930s, proponents of prohibition have insisted that cannabis must remain illegal to protect America’s children. “Protecting the children” continues to be the calculated cornerstone of anti-marijuana propaganda, the cynical centerpiece of the war on drugs.
How ironic, then, that today thousands of families in the United States are desperately seeking cannabis remedies to protect their children from deadly diseases. The erstwhile “Assassin of Youth” has become the savior for kids with catastrophic seizure disorders and other life-threatening conditions.”
“Migration and differentiation of mesenchymal stem cells (MSCs) are known to be involved in various regenerative processes such as bone healing.
The present study therefore focussed on cannabinoids which have been demonstrated to exhibit tissue healing properties…
Collectively, this study demonstrates CBD to promote the migration of MSCs via activation of the CB2 receptor and inhibition of GPR55 and to induce osteoblastic differentiation. CBD may therefore recruit MSCs to sites of calcifying tissue regeneration and subsequently support bone regeneration via an osteoanabolic action on MSCs.”
“Cannabis is the medical term for marijuana. In it’s botanical form, it’s plant is called genus. Three plant forms govern the name cannabis, and have been known for their healing/medical properties since ancient times. All three types are used medically, however, they all have different results and are taken for different reasons. Although there has been much controversy over legalizing cannabis in many states through out our nation, medical experts are standing up to the challenge as scientist continue to reveal new studies indicating the importance of legalizing it strictly for medical reasons.”
“Isn’t it strange that doctors can legally administer poison in the form of chemotherapy and radiation as well as numerous toxic pharmaceuticals and yet one of nature’s medicines- found to greatly assist cancer patients- which can be prepared by any common person without harmful side effects, is illegal and can send a person to prison for its possession?
There are numerous studies, now spanning the globe, revealing the miraculous healing properties of cannabis oil and its ability to cure cancers and other ailments without poisoning the body.
Cannabis oil, or Hemp oil contains many healing benefits including a high amount of protein as well as essential fatty acids, including the harder to come by GLA’s – known to reduce inflammation and slow the growth of cancer cells. As far as essential fatty acids go, we need a particular ratio of Omega 3, Omega 6 and GLA’s in our body for good health. Omega 3 comes largely from fish, Omega 6 can be found in many of our cooking oils such as olive and sunflower, but GLA is only found in a few sources such as borage oil, spirulina and hemp. Hemp oil happens to contain the perfect 2:5:1 ratio of omega 3, 6 and GLA’s. Interesting.
As far as cancer goes, the research proof has been out there for a while…
Cannabis oil has been shown to shrink and even cure cancers in all the studies conducted without poisoning the body. Isn’t it time to give the people a safe, legal alternative to such an ailment? Let us put aside our fears and greed and support nature in being our medicine, so she can further support us in healing.”
More: http://guardianlv.com/2013/06/cannabis-cures-cancer-without-poison/