“Hepatocellular carcinoma (HCC) is the third cause of cancer-related death worldwide… few therapeutic options are available… we investigated the effects of cannabinoids–a novel family of potential anticancer agents–on the growth of HCC. We found that Δ(9)-tetrahydrocannabinol (Δ(9)-THC, the main active component of Cannabis sativa)… reduced the viability of the human HCC cell lines…cannabinoids were also able to inhibit tumor growth… Our findings may contribute to the design of new therapeutic strategies for the management of HCC.”
Anti-tumoral action of cannabinoids on hepatocellular carcinoma: role of AMPK-dependent activation of autophagy
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