Marijuana Compound Fights Cancer; Human Trials Next

(NBC) “Research shows component in medical cannabis fights cancer.”

“The “medical” bit of medical marijuana may be legitimate after all: Turns out a component of cannabis fights cancer, according to research.

Scientists at California Pacific Medical Center found that cannabidiol, or CBD, has the ability to “turn off” the DNA that causes “breast and other types of cancers” to metastasize, according to the San Francisco Chronicle.

“If this plant were discovered in the Amazon today, scientists would be falling all over each other to be the first to bring it to market,” said Dr. Donald Abrams, chief of oncology at the University of California San Francisco, which has also found science behind marijuana’s efficacy.

The drug “has been shown to reduce pain and nausea” in cancer patients, the newspaper reported. AIDS patients also swear by cannabis for its ability to allow them to eat, sleep and otherwise function.

Turns out that cannabidiol has none of the psychotropic effects of marijuana as a whole, according to the newspaper. The researchers hope to move to clinical trials on humans soon.

Cancer cells exposed to cannabidiol lost their abilities to metastasize, according to the newspaper.”

http://www.nbcbayarea.com/news/local/Marijuana-Compound-Fights-Cancer-Human-Trials-Next-170406116.html

The endocannabinoid system and rimonabant: a new drug with a novel mechanism of action involving cannabinoid CB1 receptor antagonism–or inverse agonism–as potential obesity treatment and other therapeutic use.

Abstract

“There is considerable evidence that the endocannabinoid (endogenous cannabinoid) system plays a significant role in appetitive drive and associated behaviours. It is therefore reasonable to hypothesize that the attenuation of the activity of this system would have therapeutic benefit in treating disorders that might have a component of excess appetitive drive or over-activity of the endocannabinoid system, such as obesity, ethanol and other drug abuse, and a variety of central nervous system and other disorders. Towards this end, antagonists of cannabinoid receptors have been designed through rational drug discovery efforts. Devoid of the abuse concerns that confound and impede the use of cannabinoid receptor agonists for legitimate medical purposes, investigation of the use of cannabinoid receptor antagonists as possible pharmacotherapeutic agents is currently being actively investigated. The compound furthest along this pathway is rimonabant, a selective CB(1) (cannabinoid receptor subtype 1) antagonist, or inverse agonist, approved in the European Union and under regulatory review in the United States for the treatment of obesity. This article summarizes the basic science of the endocannabinoid system and the therapeutic potential of cannabinoid receptor antagonists, with emphasis on the treatment of obesity.”

http://www.ncbi.nlm.nih.gov/pubmed/17489873

Second Self Medicated Medical Cannabis Cancer Patient Reports Cannabis Science Brand Extracts Killing Cancer Cells

“Cannabis Science, Inc. (OTCBB:CBIS.OB – News) a pioneering U.S. biotech company developing pharmaceutical cannabis (marijuana) products, is very pleased to announce a second patient suffering skin cancer is self-administering cannabis extracts in collaboration with Cannabis Science.

This patient has photo-documented dramatic results that we will be release to the public once treatment is completed and has been properly vetted by clinical biopsy.”

More: http://eon.businesswire.com/news/eon/20111212006097/en

Cannabis Science Publishes List of Over 800 Peer-Reviewed Cannabis and Cancer References From Scientists Around the World

“This list of peer-reviewed manuscripts, provides support for the anecdotal observations of an increasing number of patients claiming successful cancer treatment using medical cannabis extracts.”

“The scientific documentation of the anti-cancer and anti-metastatic properties of cannabinoids is a driving force behind behind our long-term goal, to make high quality, effective, reliable and safe cannabis extracts available to the public beyond the borders of current medical marijuana states.”

http://www.drugs.com/clinical_trials/cannabis-science-publishes-list-over-800-peer-reviewed-cannabis-cancer-references-scientists-around-12716.html

https://www.cannabisscience.com/index.php/news-media/news-archive/215-cannabis-science-publishes-list-of-over-800-peer-reviewed-cannabis-and-cancer-references-from-scientists-around-the-world

Cannabis Science Announces Critical Cancer Patient Dr. Lynnice Wedewer, Ph.D., Cured Seven Times By Medical Cannabis

“Cannabis Science Inc. a pioneering US biotech company developing pharmaceutical cannabis products, is pleased to announce that it has been contacted by Lynnice Wedewer, Ph.D. who is a 34 year multiple cancer patient survivor who has been cured of 7 of her 8 cancers in a major part because of medical cannabis.

Dr. Wedewer wishes to share her story through Cannabis Science and help our case and education towards general acceptance of medical cannabis as a natural and viable treatment for cancer.”

 More: http://www.reuters.com/article/2011/06/29/idUS207485+29-Jun-2011+BW20110629