“Chronic intestinal pseudo-obstruction (CIPO) is a rare and challenging cause of pediatric intestinal failure, requiring long-term parenteral nutrition in most cases. Despite optimal management, some patients experience chronic abdominal pain and recurrent obstructive episodes with a major impact on their quality of life.
Cannabinoids have been successfully used in some conditions. However, their use in CIPO has never been reported in the literature.
We report a case of successful use of medicinal cannabinoids in a patient with CIPO, resulting in a significant reduction of abdominal pain, vomiting, and subocclusive episodes and increased appetite and weight, without major adverse events.
Although further observations are required to consolidate these findings, this case may be helpful for other patients suffering from the same condition.”
“Cannabinoids are extracted from Cannabis sativa L. and are used for a variety of medicinal purposes.
“For many centuries, 
“Medicinal 
“Cannabis research has historically focused on the most prevalent 
“Cannabis (marijuana, weed, pot, ganja, Mary Jane) is the most commonly used federally illicit drug in the United States.
“Medicinal cannabis has received increased research attention over recent years due to loosening global regulatory changes.
“Cannabis sativa L. is an ancient medicinal plant wherefrom over 120 cannabinoids are extracted. In the past two decades, there has been increasing interest in the therapeutic potential of cannabis-based treatments for neurological disorders such as epilepsy, and there is now evidence for the medical use of cannabis and its effectiveness for a wide range of diseases.