Marijuana Medicine’s Near-Miraculous Healing Powers Require the Whole Plant—Not Just One Oil Extract

“CBD-only laws are a pretext to extend marijuana prohibition under the guise of ‘protecting the children.'”

“Ever since marijuana was banned by the federal government in the 1930s, proponents of prohibition have insisted that cannabis must remain illegal to protect America’s children. “Protecting the children” continues to be the calculated cornerstone of anti-marijuana propaganda, the cynical centerpiece of the war on drugs.

How ironic, then, that today thousands of families in the United States are desperately seeking cannabis remedies to protect their children from deadly diseases. The erstwhile “Assassin of Youth” has become the savior for kids with catastrophic seizure disorders and other life-threatening conditions.”

http://www.alternet.org/drugs/marijuana-medicines-near-miraculous-healing-powers-require-whole-plant-not-just-one-oil

AAN calls oral cannabinoids effective for MS pain, spasticity

“An expert panel organized by the American Academy of Neurology called oral cannabis extract the only complementary and alternative medicine unequivocally effective for helping patients with multiple sclerosis, specifically easing their pain and symptoms of spasticity, medicine possibly for as long as 1 year of treatment.”

http://www.clinicalpsychiatrynews.com/cme/click-for-credit-articles/single-article/aan-calls-oral-cannabinoids-effective-for-ms-pain-spasticity/6ca42663d197581d76107390a304ec4d.html

Medical Marijuana Pills May Ease Some MS Symptoms: Review

Medical Marijuana Pills May Ease Some MS Symptoms: Review

“Medical marijuana pills and sprays might ease the symptoms of multiple sclerosis, but most other alternative therapies do little to lessen the pain and muscle rigidity that often accompanies the disease, according to new guidelines.

To reach that conclusion, an expert panel from the American Academy of Neurology reviewed more than 40 years of research on alternative medicine treatments for multiple sclerosis (MS)…

The guidelines are published in the March 25 issue of the journal Neurology.”

http://consumer.healthday.com/public-health-information-30/marijuana-news-759/guideline-medical-marijuana-may-ease-some-ms-symptoms-686096.html#.UzDKXsAnP9M.twitter

“Marijuana May Ease Some Symptoms of MS, New Guidelines Find. Medical marijuana pills or an oral spray made from cannabis may help ease some of the painful spasms caused by multiple sclerosis that make day-to-day life hard for patients, according to new guidelines from the American Academy of Neurology.” http://www.nbcnews.com/health/health-news/marijuana-may-ease-some-symptoms-ms-new-guidelines-find-n60626


Cannabidiol-2′,6′-dimethyl ether, a cannabidiol derivative, is a highly potent and selective 15-lipoxygenase inhibitor.

“Cannabidiol (CBD), one of the major components of marijuana, is known to inhibit LOX activity…

15-LOX is suggested to be involved in development of atherosclerosis, and CBDD may be a useful prototype for producing medicines for atherosclerosis.”

http://dmd.aspetjournals.org/content/37/8/1733.long

“15-lipoxygenase inhibitors as anti-atherosclerosis agents.”  http://www.ncbi.nlm.nih.gov/pubmed/18465533

Hemp (Cannabis sativa L.) seed oil: Analytical and phytochemical characterization of unsaponifiable fraction.

“Non-drug varieties of Cannabis sativa L., collectively known as “hemp”, have been an important source of food, fiber and medicince for thousands of years. The ever-increasing demand for vegetables oils has made it essential to characterize additional vegetable oil through innovative uses of its components…

This study is an important contribution for Cannabis sativa L. valorization as a source of bioactive compounds contributing to research novel applications for hemp seed oil in the food, pharmaceutical, cosmetic and other non-food industries.”

http://www.ncbi.nlm.nih.gov/pubmed/24422510

Cannabis Finds Its Way into Treatment of Crohn’s Disease.

“In ancient medicine, cannabis has been widely used to cure disturbances and inflammation of the bowel. A recent clinical study now shows that the medicinal plant Cannabis sativa has lived up to expectations and proved to be highly efficient in cases of inflammatory bowel diseases.

In a prospective placebo-controlled study, it has been shown what has been largely anticipated from anecdotal reports, i.e. that cannabis produces significant clinical benefits in patients with Crohn’s disease. The mechanisms involved are not yet clear but most likely include peripheral actions on cannabinoid receptors 1 and 2, and may also include central actions.”

http://www.ncbi.nlm.nih.gov/pubmed/24356243

“In their prospective study, Naftali et al. used THC-free Cannabis as placebo with no other cannabinoids present. However, we should consider that also other ingredients of Cannabis, such as cannabidiol, cannabigerol, and tetrahydrocannabivarine (THCV), all of them non-psychotropic components of Cannabis, have proven antiinflammatory effects in experimental intestinal inflammation. Their actions partly involve non-CB receptor mechanisms via, for instance, peroxisome proliferator-activated receptors (PPAR) and transient receptor potential cation channels subfamily V receptors (TRPV) and should be regarded as additive beneficial effects of Cannabis in the improvement of colitis in addition to THC-mediated effects.

 …an 8-week treatment with THC-rich Cannabis caused a decrease of the Crohn’s disease activity index (CDAI) in 90% of patients without producing significant side effects…

In summary, in agreement with the ancient use of Cannabis in intestinal disturbances and one decade of animal research, Cannabis was shown in a clinical trial to reduce symptoms in patients with CD. This elegant translation should be followed by larger trials confirming these results and by trials establishing the involved mechanisms to open a promising direction for future treatment of IBD.”

Full-text: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076530/

Non-Hallucinogenic Cannabinoids Could Cure Cancer: Is A Cheap Anti-Cancer Drug On The Way?

Non-Hallucinogenic Cannabinoids

“Studies that support marijuana’s medicinal properties are met with a great deal of skepticism due to cannabis’ hallucinogenic effects. Researchers from St. George’s University of London have isolated six non-hallucinogenic cannabinoids that could lead to the development of effective anti-cancer medication.

“This study is a critical step in unpicking the mysteries of cannabis as a source of medicine,” explained the study’s lead researcher, Dr. Wai Liu. “The cannabinoids examined have minimal, if any, hallucinogenic side effects, and their properties as anti-cancer agents are promising.””

More: http://www.medicaldaily.com/non-hallucinogenic-cannabinoids-could-cure-cancer-cheap-anti-cancer-drug-way-259962

Cannabidiol in Humans-The Quest for Therapeutic Targets.

“Cannabidiol (CBD), a major phytocannabinoid constituent of cannabis, is attracting growing attention in medicine for its anxiolytic, antipsychotic, antiemetic and anti-inflammatory properties.

However, up to this point, a comprehensive literature review of the effects of CBD in humans is lacking. The aim of the present systematic review is to examine the randomized and crossover studies that administered CBD to healthy controls and to clinical patients.

A systematic search was performed in the electronic databases PubMed and EMBASE using the key word “cannabidiol”. Both monotherapy and combination studies (e.g., CBD + ∆9-THC) were included. A total of 34 studies were identified: 16 of these were experimental studies, conducted in healthy subjects, and 18 were conducted in clinical populations, including multiple sclerosis (six studies), schizophrenia and bipolar mania (four studies), social anxiety disorder (two studies), neuropathic and cancer pain (two studies), cancer anorexia (one study), Huntington’s disease (one study), insomnia (one study), and epilepsy (one study).

Experimental studies indicate that a high-dose of inhaled/intravenous CBD is required to inhibit the effects of a lower dose of ∆9-THC. Moreover, some experimental and clinical studies suggest that oral/oromucosal CBD may prolong and/or intensify ∆9-THC-induced effects, whereas others suggest that it may inhibit ∆9-THC-induced effects.

Finally, preliminary clinical trials suggest that high-dose oral CBD  may exert a therapeutic effect for social anxiety disorder, insomnia and epilepsy, but also that it may cause mental sedation. Potential pharmacokinetic and pharmacodynamic explanations for these results are discussed.”

http://www.ncbi.nlm.nih.gov/pubmed/24281562

New Study: Cannabis May Help Cure Cancer

“A recent study shows that cannabis, at least its non-hallucinogenic elements, could serve as a valuable ally in not only treating cancer patients suffering from a myriad of debilitating symptoms, but it could also cure them of the deadly disease.

According to researchers at St. George Hospital Medical School, a subsidiary of the University of London, there is significant evidence that suggests certain cannabinoids found in marijuana could be used as a highly effective anti-cancer drug without patients being forced to experience the psychotropic effects of its use.

“This study is a critical step in unpicking the mysteries of cannabis as a source of medicine,” said Dr. Wai Liu, lead author of this research. “The cannabinoids examined have minimal, if any, hallucinogenic side effects, and their properties as anti-cancer agents are promising. These agents are able to interfere with the development of cancerous cells, stopping them in their tracks and preventing them from growing. In some cases, by using specific dosage patterns, they can destroy cancer cells on their own.””

More: http://www.hightimes.com/read/new-study-cannabis-may-help-cure-cancer

Cannabis might be a better treatment for epilepsy sufferers -msn

Young marijuana plants (©AP Photo/Ted S. Warren)

“Cannabis is now apparently the cure for everything from cancer,  diarrhea, bipolar disorder and Multiple sclerosis, to an ailing economy and being a smart aleck teenager. The latest chronic illness to get the 4:20 treatment is epilepsy. British scientists from the University of Reading tested a compound in pot called cannabidivarin on rats and mice with six types of epilepsy, and found it “strongly suppressed seizures” without the unpleasant side effects of current anti-epilepsy drugs. With 1 percent of the world’s population suffering from the disease, the head of the research team, Ben Whalley, says there’s a pressing need for better treatments. “It’s a chronic condition with no cure and currently, in around one-third of cases, the currently available treatments do not work, cause serious side effects and increase fatalities,” he said.”

http://now.msn.com/epilepsy-treatment-found-in-cannabis-may-prove-better-than-current-methods