“α-Glucosidase inhibitory assay-guided isolation of the aqueous extract from Cannabis sativa leaves afforded three new compounds named cannabisaldehyde (8), cannacone A (9), and canniprene C (10), along with eight previously known compounds (1–7, 11). The structures of new compounds were determined through extensive analysis of various spectroscopic data. Of isolated compounds, cannacone A (9) demonstrated most potent inhibition against maltase and sucrase with IC50 values of 80.0 and 82.9 μM, respectively. Cannacone A (9) inhibited both maltase and sucrase by competitive mechanism.”
https://pubmed.ncbi.nlm.nih.gov/39756038/
https://www.tandfonline.com/doi/full/10.1080/14786419.2024.2448841
“Alpha-glucosidase inhibitors (AGIs) are used to treat type 2 diabetes and to prevent or delay the development of type 2 diabetes in people at risk.”
“Alpha-glucosidase inhibitors are antihyperglycemic agents that lower blood glucose by delaying the digestion and absorption of complex carbohydrates.”